Alangium
Alangium
Alangium is a genus of plants traditionally used in various Asian cultures for its purported medicinal properties, though specific uses are not well-documented. Scientific studies have shown that compounds isolated from Alangium species exhibit anti-proliferative and migration-inhibiting effects on certain cell lines, as well as significant antioxidant, antidiabetic, and hypolipidemic activities when tested in combination with other plants like Ocimum sanctum. Both Carapichea ipecacuanha and Alangium salviifolium are involved in the biosynthesis of ipecac alkaloids through a nonenzymatic Pictet-Spengler reaction, but they use different monoterpene precursors. The study also identified organ-specific bioactive metabolites in extracts from Alangium salviifolium that showed varying concentrations and cytotoxicity against A431 cells. To date, no major safety issues or drug interactions have been recorded for Alangium.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Die Studie erkannte organspezifische biologisch aktive Metabolite in Alangium salviifolium-Extrakten und zeigte verschiedene Konzentrationen sowie Zytotokсizität gegenüber A431-Zellen.
- Die Studie zeigte, dass extrakte aus Alangium salvifolium und Ocimum sanctum sowohl einzeln als auch kombiniert signifikante antioxidantische, antidiabetische und hypolipidemische Aktivitäten aufweisen.
- Beide Arten Carapichea ipecacuanha und Alangium salviifolium initiieren die Biosynthese von Ipecac-Alkaloiden durch eine nichtenzymatische Pictet-Spengler-Reaktion, obwohl sie unterschiedliche Monoterpen-Predromane verwenden.
- Mansonone E, isolated from Alangium platanifolium, showed notable anti-proliferative and migration-inhibiting effects on SW620 cells.
Frequently asked questions
What is Alangium?
Alangium (Alangium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Alangium?
4 sourced findings are recorded for Alangium; the strongest carries evidence grade D. For example: Die Studie erkannte organspezifische biologisch aktive Metabolite in Alangium salviifolium-Extrakten und zeigte verschiedene Konzentrationen sowie Zytotokсizität gegenüber A431-Zellen.
How strong is the evidence for Alangium?
The strongest finding for Alangium carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Alangium safe? What are the side effects?
No major safety issues are recorded for Alangium in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Alangium interact with medications?
No drug interactions are recorded for Alangium in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Alangium?
Alangium is also known as: Алангиум.
Is Alangium a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Ipecac alkaloid biosynthesis in two evolutionarily distant plants. literature abstract metadata
- T2 Synergistic evaluation of anti-diabetic and hypolipidemic effects of Alangium salvifolium and Ocimum sanctum extracts. literature abstract metadata
- T2 Cadinane sesquiterpenes from Alangium platanifolium: structural elucidation and anti-colorectal cancer biological evaluation. literature abstract metadata
- T2 Multi-technique comparative analysis of bioactive metabolites in Alangium salviifolium (L.f.) Wangerin leaf, fruit and seed extracts using UV-Vis, FTIR, HPLC, LCMS and cytotoxicity evaluation on A431 cell line. literature abstract metadata