FolkKB

Labisia pumila

Labisia pumila

Labisia pumila, a plant traditionally used primarily in Malaysian folk medicine, has shown promise across various scientific studies. It is traditionally employed for respiratory and gastrointestinal conditions but lacks specific documented uses in traditional practices. Scientific evidence suggests that Labisia pumila standardized extract (SKF7®) may aid in weight management by reducing body weight, BMI, waist circumference, and waist-to-height ratio in individuals with obesity. Additionally, the polysaccharides from this plant have been shown to increase lifespan and improve stress tolerance in nematodes and fruit flies, indicating potential anti-aging benefits. Labisia pumila var. alata extract has demonstrated apoptosis induction in MCF-7 breast cancer cells by inhibiting oestrogen receptor activity, suggesting possible applications in oncology research. The extract also showed potential anti-SARS-CoV-2 and anti-inflammatory activities in vitro, indicating broad biological effects. No major safety concerns or drug interactions have been recorded to date, but further research is needed to fully understand its efficacy and safety profile.

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Beste Evidenz
B
Warnhinweise
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Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.

Was die Wissenschaft sagt

  • Polysaccharide von Labisia pumila erhöhen das Lebensalter und verbessern den Stressausgleich bei C. elegans und D. melanogaster. D PMID
  • Das Extrakt von Labisia pumila var. alata verursacht Apoptose bei MCF-7-Tumorzellen des Brustgewebes durch die Inhibition der Östrogenrezeptoraktivität. D PMID
  • Die Studie zeigte, dass SKF7® potentielle antivirale und entzündungshemmende Aktivitäten in vitro aufweist. D PMID
  • Die Studie zeigte an, dass der standardisierte Extrakt von Labisia pumila (SKF7®) einen statistisch signifikanten Rückgang des prozentualen Gewichtsverlustes, des BMI, der Taille und des Verhältnisses Taille/Höhe bei Individuen mit Adipositas aufweist. B PMID

Frequently asked questions

What is Labisia pumila?

Labisia pumila (Labisia pumila) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Labisia pumila?

4 sourced findings are recorded for Labisia pumila; the strongest carries evidence grade B. For example: Polysaccharide von Labisia pumila erhöhen das Lebensalter und verbessern den Stressausgleich bei C. elegans und D. melanogaster.

How strong is the evidence for Labisia pumila?

The strongest finding for Labisia pumila carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Labisia pumila safe? What are the side effects?

No major safety issues are recorded for Labisia pumila in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Labisia pumila interact with medications?

No drug interactions are recorded for Labisia pumila in our sources. This does not rule them out — check with a pharmacist.

Is Labisia pumila a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Quellen

  1. T2 Labisia pumila standardized extract (SKF7®) reduces percentage of waist circumference and waist-to-height ratio in individuals with obesity. literature abstract metadata
  2. T2 In vitro study on efficacy of SKF7®, a Malaysian medicinal plant product against SARS-CoV-2. literature abstract metadata
  3. T2 Labisia pumila var. alata Extract Induces Apoptosis Cell Death by Inhibiting the Activity of Oestrogen Receptors in MCF-7 Breast Cancer Cells. literature abstract metadata
  4. T2 Polysaccharide-mediated aging-modulatory effects of Labisia Pumila extracts on the physiological changes in C. elegans and D. melanogaster. literature abstract metadata