Caterpillar Fungus

Ophiocordyceps sinensis

Ophiocordyceps sinensis, traditionally known as caterpillar fungus or冬虫夏草 (dōng chóng xià cǎo) in Chinese, is a traditional medicine with roots in Tibetan and Chinese herbal practices. It has been used for various purposes including enhancing vitality and treating respiratory issues, though specific recorded uses are limited. Scientific evidence suggests that Ophiocordyceps sinensis may have potential anticancer effects through mechanisms such as apoptosis induction and immune modulation; however, these findings are based on preclinical models and require further clinical validation. Additionally, cordycepin from a related species, Cordyceps militaris, has shown improvements in fasting glucose and lipid profiles in mice fed a high-fat diet, possibly due to changes in AMPK/SREBP-1c signaling pathways. Key metabolites and signaling pathways for prehypha development in Ophiocordyceps sinensis have been identified, including Sodium Danshensu. A study also validated an immunomodulatory peptide, WALGT, from the fungus. Safety concerns are currently minimal as no major issues have been recorded; similarly, there are no reported drug interactions at present.

Auf einen Blick
Beste Evidenz
D
Warnhinweise

Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.

Was die Wissenschaft sagt

  • Cordycepine aus Cordyceps militaris verbesserte bei Mäusen mit einer fettreichen Ernährung das Fasting-Glucose- und Lipidprofil, was mit Änderungen in der AMPK/SREBP-1c-Signalwege assoziiert ist. D PMID
  • Schlüsselmetabolite und Signalwege für das Prähyphenentwicklung in Ophiocordyceps sinensis wurden identifiziert, einschließlich Sodii Danshensu. D PMID
  • Ophiocordyceps sinensis zeigte in vorlaboratorischen Modellen versprechenbe Antitumoreffekte durch mehrere Mechanismen einschließlich Apoptose-Induktion und Immunmodulation, aber weitere klinische Studien sind notwendig. D PMID
  • Die Studie identifizierte und validierte ein immunmodulierendes Peptid, WALGT, in Ophiocordyceps sinensis. D PMID

Frequently asked questions

What is Caterpillar Fungus?

Caterpillar Fungus (Ophiocordyceps sinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Caterpillar Fungus?

4 sourced findings are recorded for Caterpillar Fungus; the strongest carries evidence grade D. For example: Cordycepine aus Cordyceps militaris verbesserte bei Mäusen mit einer fettreichen Ernährung das Fasting-Glucose- und Lipidprofil, was mit Änderungen in der AMPK/SREBP-1c-Signalwege assoziiert ist.

How strong is the evidence for Caterpillar Fungus?

The strongest finding for Caterpillar Fungus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Caterpillar Fungus safe? What are the side effects?

No major safety issues are recorded for Caterpillar Fungus in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Caterpillar Fungus interact with medications?

No drug interactions are recorded for Caterpillar Fungus in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Caterpillar Fungus?

Caterpillar Fungus is also known as: кордицепс китайский.

Is Caterpillar Fungus a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Quellen

  1. T2 Discovery of functional compounds from dimorphic edible Ophiocordyceps sinensis fungus in host haemolymph. literature abstract metadata
  2. T2 Comparative computational analysis of the hypolipidaemic potential of Cordyceps militaris and Ophiocordyceps sinensis, with in vivo validation of cordycepin. literature abstract metadata
  3. T2 Peptidomics-based identification of endogenous free peptides from Ophiocordyceps sinensis and functional validation of immunomodulatory peptide WALGT. literature abstract metadata
  4. T2 Ophiocordyceps sinensis in Cancer Therapy: Bridging Traditional Medicine and Modern Oncology. literature abstract metadata