Devil's tongue
Amorphophallus konjac
Amorphophallus konjac, a plant native to East Asia, is traditionally used in some folk remedies but lacks extensive documented use. Scientific evidence suggests that KūlarisTM, derived from Amorphophallus konjac, may reduce acne severity and improve quality of life for individuals with mild-to-severe acne; however, the strength of this evidence is moderate due to limited studies. Additionally, research indicates that certain compounds in AkNBS-LRR43 and AkNBS-LRR100 from Amorphophallus konjac can enhance immune response against bacteria by boosting antioxidant activity. Furthermore, konjac petroleum ether extract has shown potential in inhibiting the migration and invasion of triple-negative breast cancer cells through modulation of OLFML2A to inhibit epithelial-to-mesenchymal transition (EMT). Notably, no major safety concerns or drug interactions have been recorded for Amorphophallus konjac.
- Mejor evidencia
- B
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- AkNBS-LRR43 y AkNBS-LRR100 regulan positivamente la inmunidad en Amorphophallus konjac frente a Pectobacterium carotovorum subsp. carotovorum al aumentar la actividad antioxidante.
- El extracto de petróleo de konjac inhibe la migración e invasión de las células del cáncer de mama negativo triple regulando OLFML2A para inhibir la EMT.
- Este estudio identificó 11 miembros de la familia AkLOX en Amorphophallus konjac y encontró sus patrones de expresión bajo diversos estrés.
- Kūlaris显著减少了痤疮的严重程度和数量，改善了生活质量，并且在轻至中度痤疮患者中耐受性良好。
Frequently asked questions
What is Devil's tongue?
Devil's tongue (Amorphophallus konjac) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Devil's tongue?
4 sourced findings are recorded for Devil's tongue; the strongest carries evidence grade B. For example: AkNBS-LRR43 y AkNBS-LRR100 regulan positivamente la inmunidad en Amorphophallus konjac frente a Pectobacterium carotovorum subsp. carotovorum al aumentar la actividad antioxidante.
How strong is the evidence for Devil's tongue?
The strongest finding for Devil's tongue carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Devil's tongue safe? What are the side effects?
No major safety issues are recorded for Devil's tongue in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Devil's tongue interact with medications?
No drug interactions are recorded for Devil's tongue in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Devil's tongue?
Devil's tongue is also known as: Аморфофаллус коньяк.
Is Devil's tongue a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Safety and Clinical Efficacy of KūlarisTM, an Herbal Supplement for Mild to Severe Acne Vulgaris - A 12-Week Randomized, Double Blind, Placebo-Controlled Study. literature abstract metadata
- T2 Identification of the AkLOX gene family in Amorphophallus konjac and analysis of its expression patterns under different treatments. literature abstract metadata
- T2 Konjac petroleum ether extract inhibits triple-negative breast cancer cell migration and invasion by attenuating OLFML2A-mediated epithelial-mesenchymal transition. literature abstract metadata
- T2 Identification of the NBS-LRR gene family and AkNBS-LRR43 and 100 functional analysis under biotic stress. literature abstract metadata