FolkKB

Dendropanax morbiferus

Dendropanax morbiferus

Dendropanax morbiferus, also known as Heishen or Black参 (Bān Xiān), is a traditional medicine plant native to East Asia. While its use in traditional practices has not been extensively documented, studies have shown promising results. Scientific evidence suggests that Dendropanax morbiferus may improve cognitive function and enhance memory, possibly due to increased cortical thickness in the left lingual gyrus/cuneus. Additionally, it demonstrated significant antioxidant and anti-inflammatory effects in vitro, reducing joint swelling in a rheumatoid arthritis mouse model. In skin cells, the extract reduced reactive oxygen species (ROS) production and inhibited MMP-1 expression, indicating potential antiaging benefits. Moreover, Dendropanax morbiferus leaf extract significantly inhibited breast cancer cell proliferation and induced apoptosis via the MAPK pathway both in vitro and in vivo. No major safety concerns or known drug interactions have been recorded for this plant.

De un vistazo
Mejor evidencia
B
Precauciones
—

Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.

Lo que dice la ciencia

  • Este estudio encontró que Dendropanax morbiferus mejoró la atención, la memoria y las funciones cognitivas globales, asociado con una mayor grosor de corteza en el giro lingual izquierdo/cuneus. B PMID
  • DMWE mostró efectos antioxidantes y antiinflamatorios significativos in vitro y redujo la hinchazón articular en un modelo de ratas con artritis reumatoide. D PMID
  • El DP redujo significativamente la producción de especies reactivas de oxígeno (ROS) e inhibió la expresión de MMP-1, lo que sugiere posibles efectos antienvejecimiento en las células cutáneas. D PMID
  • El extracto de hoja de Dendropanax morbiferus inhibió significativamente la proliferación de las células del cáncer de mama MDA-MB-231 y indujo apoptosis a través del camino MAPK tanto in vitro como in vivo. D PMID
  • El extracto de Dendropanax morbiferus mejoró los parámetros del sueño en modelos de drosophila y ratones a través de un aumento de los niveles de GABA y serotonina y una actividad antioxidante aumentada. D PMID

Frequently asked questions

What is Dendropanax morbiferus?

Dendropanax morbiferus (Dendropanax morbiferus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Dendropanax morbiferus?

5 sourced findings are recorded for Dendropanax morbiferus; the strongest carries evidence grade B. For example: Este estudio encontró que Dendropanax morbiferus mejoró la atención, la memoria y las funciones cognitivas globales, asociado con una mayor grosor de corteza en el giro lingual izquierdo/cuneus.

How strong is the evidence for Dendropanax morbiferus?

The strongest finding for Dendropanax morbiferus carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Dendropanax morbiferus safe? What are the side effects?

No major safety issues are recorded for Dendropanax morbiferus in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Dendropanax morbiferus interact with medications?

No drug interactions are recorded for Dendropanax morbiferus in our sources. This does not rule them out — check with a pharmacist.

Is Dendropanax morbiferus a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Fuentes

  1. T2 Dendropanax morbiferus H. Lév. Leaf Extract Inhibits the Proliferation of MDA-MB-231 Breast Cancer Cells and Induces Apoptosis via the MAPK Pathway In Vitro and In Vivo. literature abstract metadata
  2. T2 Effects of Dendropanax morbiferus Leaf Extract on Sleep Parameters in Invertebrate and Vertebrate Models. literature abstract metadata
  3. T2 Evaluation of the Antiaging Potential of the Dendropanax morbiferus-Derived Compound Dendropanoxide in TNF-α-Stimulated Human Dermal Fibroblasts. literature abstract metadata
  4. T2 The effects of Dendropanax morbiferus on cognitive function and cerebral cortical thickness: A randomized, double-blind, placebo-controlled trial. literature abstract metadata
  5. T2 The Therapeutic Effects of Dendropanax morbiferus Lév. Water Leaf Extracts in a Rheumatoid Arthritis Animal Model. literature abstract metadata