Devil's Bit
Ruellia tuberosa
Ruellia tuberosa, a plant traditionally used in various folk medicine practices but with no specific documented traditional uses, has shown promising results in scientific research. Studies have indicated that Ruellia tuberosa-derived zinc oxide nanoparticles exhibit significant cytotoxicity towards prostate cancer cells while sparing normal cells, potentially via p53 and STAT3 signaling pathways. Additionally, the ethanolic extract of Ruellia tuberosa showed potential memory improvement and reduced oxidative stress and inflammation in a rodent model for Alzheimer's disease. The plant also demonstrated moderate levels of chlorophyll and phenolic content in its stems among twenty medicinal weeds investigated. Safety-wise, no major issues have been recorded, and there are currently no known drug interactions associated with Ruellia tuberosa.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- nanopartículas de óxido de zinc derivadas de Ruellia tuberosa indujeron apoptosis en células de cáncer de próstata a través de vías de señalización p53 y STAT3.
- Ruellia tuberosa presentaba niveles moderados de clorofila y flavonoides en sus tallos entre las veinte hierbas medicinales estudiadas.
- Ruellia tuberosa ethanolic extract showed potential in improving cognitive functions and reducing oxidative stress and inflammation in an Alzheimer's disease model, but more research is needed.
- Este estudio desarrolló hidrogel con extracto de Ruellia tuberosa con posibles propiedades antibacterianas, antioxidantes y para la curación de heridas.
Frequently asked questions
What is Devil's Bit?
Devil's Bit (Ruellia tuberosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Devil's Bit?
4 sourced findings are recorded for Devil's Bit; the strongest carries evidence grade D. For example: nanopartículas de óxido de zinc derivadas de Ruellia tuberosa indujeron apoptosis en células de cáncer de próstata a través de vías de señalización p53 y STAT3.
How strong is the evidence for Devil's Bit?
The strongest finding for Devil's Bit carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Devil's Bit safe? What are the side effects?
No major safety issues are recorded for Devil's Bit in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Devil's Bit interact with medications?
No drug interactions are recorded for Devil's Bit in our sources. This does not rule them out — check with a pharmacist.
Is Devil's Bit a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 An investigation of the pigments, antioxidants and free radical scavenging potential of twenty medicinal weeds found in the southern part of Bangladesh. literature abstract metadata
- T2 Optimized production of carboxymethyl cellulose/guar gum based durable hydrogel for in vitro performance assessment. literature abstract metadata
- T2 Pharmacological Characterization of Ruellia tuberosa Ethanolic Extract in a Rodent Model of Cognitive Impairment. literature abstract metadata
- T2 Fabrication of zinc oxide nanoparticles using Ruellia tuberosa leaf extract induces apoptosis through P53 and STAT3 signalling pathways in prostate cancer cells. literature abstract metadata