Conker-tree
Aesculus hippocastanum
Aesculus hippocastanum，通常被称为马栗树，是一种具有欧洲和亚洲草药医学渊源的传统植物。传统上，它并没有广泛用于特定的医疗目的；然而，它的树皮和种子在民间疗法中被用来治疗各种状况，如静脉曲张和腿部溃疡。科学研究表明，基于Aesculus hippocastanum的纳米胶囊对测试的植物提取物中的念珠菌属表现出选择性的抗真菌活性。此外，与替莫唑胺结合的提取物显示出显著降低胶质母细胞瘤细胞活力，这可能通过调节Wnt/β-连环蛋白途径具有潜在的抗癌应用。研究还表明，Aesculus hippocastanum 可能通过破坏Nrf2/PRDX6/GPX4途径诱导肝细胞铁死亡，从而表明其在肝脏损伤治疗中的潜在用途。值得注意的是，Kalmusia variispora 被鉴定为影响马栗树的病原体，但似乎对人类健康或医疗应用没有直接影响。Aesculus hippocastanum 没有记录到重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 基于Aesculus hippocastanum的纳米囊在测试的植物提取物中对念珠菌属表现出选择性活性。
- Aesculus hippocastanum 提取物与替莫唑胺联合显著降低了胶质母细胞瘤细胞的活力并促进了通过调节 Wnt/β-连环蛋白途径的凋亡。
- SA通过破坏Nrf2/PRDX6/GPX4途径诱导肝细胞铁死亡，表明SA引起的肝损伤可能存在潜在的治疗靶点。
- Kalmusia variispora 被确认为导致悬铃木树皮腐烂和枝条枯死的原因（Aesculus hippocastanum L.）。
Frequently asked questions
What is Conker-tree?
Conker-tree (Aesculus hippocastanum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Conker-tree?
4 sourced findings are recorded for Conker-tree; the strongest carries evidence grade D. For example: 基于Aesculus hippocastanum的纳米囊在测试的植物提取物中对念珠菌属表现出选择性活性。
How strong is the evidence for Conker-tree?
The strongest finding for Conker-tree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Conker-tree safe? What are the side effects?
No major safety issues are recorded for Conker-tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Conker-tree interact with medications?
No drug interactions are recorded for Conker-tree in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Conker-tree?
Conker-tree is also known as: конский каштан обыкновенный.
Is Conker-tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Modulation of Wnt/β-Catenin Pathway by Aesculus hippocastanum Extract Enhances Temozolomide Sensitivity in Glioblastoma Cells. literature abstract metadata
- T2 Hyaluronic-Acid Nanocapsules with Plant Extracts: Characterization and Antimicrobial Activity Against Skin Microbiota. literature abstract metadata
- T2 Sodium aescinate induces hepatocyte ferroptosis through the Nrf2/PRDX6/GPX4 axis. literature abstract metadata
- T2 First Report of Kalmusia variispora Causing Bark Necrosis and Branch Dieback of Horse Chestnut (Aesculus hippocastanum L.). literature abstract metadata