FolkKB

Grains of paradise

Aframomum melegueta

Aframomum melegueta，又称鳄梨胡椒或天堂籽，是西非的传统药用植物。其在特定医疗实践中的使用记录并不广泛；然而它具有历史意义并在该地区有烹饪用途。科学研究表明，Aframomum melegueta 的种子可能改善认知功能，在接受颠茄碱治疗的小鼠中观察到 A. melegueta 比 A. danielli 更有效。此外，这些种子通过微生物生物转化活性化合物显示出潜在的肾保护作用，这由 AMPK 结合亲和力表明。此外，Aframomum melegueta 种子粉末被观察到在暴露于黄曲霉毒素 B₁ 的肉鸡中恢复生长性能和肝功能，并减轻热应激对肉鸡的影响，包括生产率下降、氧化应激、免疫功能障碍和炎症。与该植物相关的重大安全问题或药物相互作用尚未记录。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Aframomum melegueta 和 Aframomum danielli 的种子在用颠茄碱处理的大鼠中改善了认知功能，其中A. melegueta 更具有效性。 D PMID
  • Aframomum melegueta的生物活性化合物的微生物生物转化产生了具有潜在肾保护作用的代谢物，如AMPK结合亲和力所示。 D PMID
  • Aframomum melegueta种子粉补充部分或完全恢复了暴露于aflatoxin B1的肉鸡的生长性能和肝功能。 D PMID
  • 在每千克1,000毫克的剂量下，食用鳄鱼胡椒种子粉可减轻热应激诱导的性能抑制、氧化应激、免疫功能障碍和肉鸡的炎症。 D PMID

Frequently asked questions

What is Grains of paradise?

Grains of paradise (Aframomum melegueta) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Grains of paradise?

4 sourced findings are recorded for Grains of paradise; the strongest carries evidence grade D. For example: Aframomum melegueta 和 Aframomum danielli 的种子在用颠茄碱处理的大鼠中改善了认知功能，其中A. melegueta 更具有效性。

How strong is the evidence for Grains of paradise?

The strongest finding for Grains of paradise carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Grains of paradise safe? What are the side effects?

No major safety issues are recorded for Grains of paradise in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Grains of paradise interact with medications?

No drug interactions are recorded for Grains of paradise in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Grains of paradise?

Grains of paradise is also known as: Maniguette.

Is Grains of paradise a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Neuroprotective effects of dietary inclusions of alligator pepper (Aframomum melegueta) and bastard melegueta (Aframomum danielli) seeds on scopolamine-induced amnesia in rats. literature abstract metadata
  2. T2 In silico nephroprotective evaluation of microbial biotransformed metabolites from Aframomum melegueta. literature abstract metadata
  3. T2 Dietary melegueta seed powder modulates growth, hepatic function, and biomarkers to counteract aflatoxin B₁ toxicity in broilers. literature abstract metadata
  4. T2 Dietary alligator pepper powder mitigates thermal stress-induced performance suppression, immune dysfunction, and cellular stress in broiler chickens reared under hot-humid tropical conditions. literature abstract metadata