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Aglaia silvestris

Aglaia silvestris

Aglaia silvestris 是一种传统上没有特定药用用途的植物。科学研究在不同来源的该植物中发现了多种三萜类化合物，包括3,4-secodammaranes 和20R/20S异构体。从 Aglaia silvestris 中分离出的 silyverstrinol 和 episilvestrinsol 在体外对几种人类癌细胞系表现出强大的细胞毒性活性，表明其可能具有抗癌作用。此外，发现两种原花青素抑制了 cathepsin L 的活性，这可能会潜在地抑制 SARS-CoV-2 进入。三种萜类化合物被识别为 p53-MDM2 交互作用的潜在抑制剂。目前的研究中没有记录 Aglaia silvestris 造成的主要安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 研究在不同来源的Aglaia silvestris中鉴定出了多种三萜，包括3,4-secodammaranes和20R/20S异构体。 D PMID
  • Silvestrol 和 episilvestrol，来源于 Aglaia silvestris 的分离物，在体外对多个人类癌细胞系表现出强大的细胞毒活性。 D PMID
  • 两种原花青素寡聚体抑制猫眼蛋白L的活性，可能抑制SARS-CoV-2进入。 D PMID
  • 鉴定出三种萜类化合物可能是p53-MDM2相互作用的潜在抑制剂。 D PMID
  • 该研究更新了来自Aglaia种的rocaglate衍生物的植物化学和生物学调查，强调其作为具有抗肿瘤和抗病毒作用的先导化合物的潜力。 D PMID

Frequently asked questions

What is Aglaia silvestris?

Aglaia silvestris (Aglaia silvestris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Aglaia silvestris?

5 sourced findings are recorded for Aglaia silvestris; the strongest carries evidence grade D. For example: 研究在不同来源的Aglaia silvestris中鉴定出了多种三萜，包括3,4-secodammaranes和20R/20S异构体。

How strong is the evidence for Aglaia silvestris?

The strongest finding for Aglaia silvestris carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Aglaia silvestris safe? What are the side effects?

No major safety issues are recorded for Aglaia silvestris in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Aglaia silvestris interact with medications?

No drug interactions are recorded for Aglaia silvestris in our sources. This does not rule them out — check with a pharmacist.

Is Aglaia silvestris a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. literature abstract metadata
  2. T2 Silvaglins and related 2,3-secodammarane derivatives - unusual types of triterpenes from Aglaia silvestris. literature abstract metadata
  3. T2 Promising Terpenes as Natural Antagonists of Cancer: An In-Silico Approach. literature abstract metadata
  4. T2 Update on Phytochemical and Biological Studies on Rocaglate Derivatives from Aglaia Species. literature abstract metadata
  5. T2 Two Resveratrol Oligomers Inhibit Cathepsin L Activity to Suppress SARS-CoV-2 Entry. literature abstract metadata