FolkKB

Arctium lappa

Arctium lappa

Arctium lappa，又称刺菜，是一种传统植物，其根和种子被用于各种草药实践中。传统上，它的使用没有广泛记录；然而，在一些亚洲和欧洲民间医学中，它曾被用来治疗皮肤问题和消化不适。科学研究表明，刺菜籽粉可以作为食品成分而不显著影响活性化合物的质量或稳定性。体外研究表明，从Arctium lappa提取的arctigenin可以抑制不同亚型乳腺癌细胞的增殖，并在动物模型中显著抑制肿瘤生长，且未报告毒性。此外，arctigenin（ATG）已被发现通过调节与氧化应激和炎症相关的代谢途径来改善肾功能并减少纤维化。迄今为止，Arctium lappa尚未记录有重大安全问题或药物相互作用，但进一步研究对于完全了解其潜在益处和应用是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 使用超临界CO2脱脂的牛蒡籽粉可以不显著影响感官质量和主要酚类化合物稳定性的情况下，被纳入姜饼中。 D PMID
  • 研究发现，来源于刺儿菜（Arctium lappa）的阿卡提苷通过POU2F1/GRB10轴抑制软骨细胞焦亡从而缓解骨关节炎疼痛。 D PMID
  • 弧抑制了多种乳腺癌亚型的细胞增殖，并在体内显著抑制肿瘤生长，且无明显毒性。 D PMID
  • ATG 改善肾功能并减少纤维化，通过调节 TCA 循环和氧化磷酸化损伤的 S100A8/A9/NOX/NF-κB 信号通路。 D PMID
  • ALEO 在体外对多种世卫组织优先病原体显示出强大的抗菌活性。 D PMID

Frequently asked questions

What is Arctium lappa?

Arctium lappa (Arctium lappa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Arctium lappa?

5 sourced findings are recorded for Arctium lappa; the strongest carries evidence grade D. For example: 使用超临界CO2脱脂的牛蒡籽粉可以不显著影响感官质量和主要酚类化合物稳定性的情况下，被纳入姜饼中。

How strong is the evidence for Arctium lappa?

The strongest finding for Arctium lappa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Arctium lappa safe? What are the side effects?

No major safety issues are recorded for Arctium lappa in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Arctium lappa interact with medications?

No drug interactions are recorded for Arctium lappa in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Arctium lappa?

Arctium lappa is also known as: Лопух большой, Bardane commune.

Is Arctium lappa a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Effects of Gingerbread Cookie Enrichment with Native and Supercritical CO2-Defatted Burdock Seeds. literature abstract metadata
  2. T2 In silico and in vitro assessment of antimicrobial activity of Arctium lappa L. leaf and flower essential oil against WHO priority pathogens. literature abstract metadata
  3. T2 Preliminary Study on the Mechanism of Arctigenin in Alleviating Osteoarthritis Pain by Suppressing Chondrocyte Pyroptosis: The Potential Role of the POU2F1/GRB10 Axis. literature abstract metadata
  4. T2 Elucidating the therapeutic efficacy and mechanisms of arctigenin in ameliorating renal fibrosis: a combined transcriptomic and proteomic study. literature abstract metadata
  5. T2 Arctigenin Suppresses Breast Cancer Growth In Vitro and In Vivo Through Subtype-Specific Multi-Targeting Activity. literature abstract metadata