Belladonna

Atropa

阿托品是一种传统上与欧洲民间传说相关并用于各种文化背景中的植物。它主要以其毒性而闻名,尽管具体的传统用途没有很好地记录下来。科学研究集中在通过代谢工程提高阿托品铃兰中氢化可待因的产量,使其比野生型植物增加了6.511 mg/g DW。此外,研究还探讨了阿托品铃兰提取物与 bifenthrin 结合使用对抗 Tetranychus urticae 蜡螨的效果,而不会对天敌产生不良影响。阿托品铃兰中 rolB 和 rolC 基因的共表达显示出了代谢拮抗作用,特别是在颠茄生物碱合成和植物形态方面。历史毒性报告强调了阿托品属物种(包括紫藤属和黑刺茄)潜在的危害性,并突显了它们记录中的使用情况以及通过食用浆果引起的中毒案例。没有记录到任何显著的安全问题或药物相互作用与阿托品有关。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • The study employed metabolic engineering to enhance hyoscyamine yield and purity in Atropa belladonna, achieving a 6.511 mg/g DW increase over wild-type plants. D PMID
  • 研究发现,阿托品颠茄提取物与避蚊胺联合使用时,对二斑红蜘蛛的杀螨效果增强且不对天敌产生负面影响。 D PMID
  • Atropa belladonna rolB 和 rolC 基因的共表达显示出代谢拮抗作用,其中 rolC 主要调节莨菪生物碱合成并影响植物形态和耐旱性。 D PMID
  • 研究发现,Atropa belladonna、Solanum dulcamara 和 Solanum nigrum 因其生物碱含量而具有显著的毒性风险,并有文献记载了因食用浆果而导致中毒的案例。 D PMID
  • 患者因残留生物碱的再吸收,在巴豆中毒后出现了晚发性抗胆碱能毒性反应。 D PMID

Frequently asked questions

What is Belladonna?

Belladonna (Atropa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Belladonna?

5 sourced findings are recorded for Belladonna; the strongest carries evidence grade D. For example: The study employed metabolic engineering to enhance hyoscyamine yield and purity in Atropa belladonna, achieving a 6.511 mg/g DW increase over wild-type plants.

How strong is the evidence for Belladonna?

The strongest finding for Belladonna carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Belladonna safe? What are the side effects?

No major safety issues are recorded for Belladonna in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Belladonna interact with medications?

No drug interactions are recorded for Belladonna in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Belladonna?

Belladonna is also known as: Красавка (растение), Atrope.

Is Belladonna a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Acaricidal Activity and Potential Application of Atropa belladonna. literature abstract metadata
  2. T2 A Case of Belladonna Poisoning With Late-Onset Reappearance of Anticholinergic Toxicity. literature abstract metadata
  3. T2 A Pull-Block Metabolic Engineering Strategy for High-Yield and High-Purity Hyoscyamine Production in Atropa belladonna. literature abstract metadata
  4. T2 Toxic Risks of Nightshade Species: A comprehensive review of the documented toxicity of Atropa belladonna, Solanum dulcamara, and Solanum nigrum. literature abstract metadata
  5. T2 Unraveling the pleiotropic functions of Rhizobium rhizogenes rolB and rolC genes on phenotype, secondary metabolism, and drought tolerance in Atropa belladonna. literature abstract metadata