Belladonna

Atropa

阿托品是一种传统上与欧洲和亚洲部分地区传统医学相关的植物。尽管其具体用途没有很好地记录,但它历史上与各种文化及民间传统有关,通常与化妆品和毒物相关,因为存在有毒的生物碱。科学研究表明,代谢工程可以提高阿托品在Atropa belladonna中的产量,从而可能改善某些应用的效果。此外,研究表明将阿托品提取物与Bifenthrin结合使用可以增加对Tetranychus urticae的杀螨活性而不损害天敌,这暗示了潜在的农业益处。然而,阿托品属植物如A. belladonna、Solanum dulcamara和Solanum nigrum因其生物碱含量而被认为具有显著的毒性风险,并且有文献记录了因食用浆果而导致中毒的案例。在文献中没有记录到重大安全问题或药物相互作用,但鉴于其潜在的毒性,应谨慎对待。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 该研究采用代谢工程来提高Atropa belladonna中羟基吗啉的产量和纯度,较野生型植物实现了6.511 mg/g DW 的增幅。 D PMID
  • 研究发现,阿托品颠茄提取物与避蚊胺联合使用时,对二斑红蜘蛛的杀螨效果增强且不对天敌产生负面影响。 D PMID
  • Atropa belladonna rolB 和 rolC 基因的共表达显示出代谢拮抗作用,其中 rolC 主要调节莨菪生物碱合成并影响植物形态和耐旱性。 D PMID
  • 研究发现,Atropa belladonna、Solanum dulcamara 和 Solanum nigrum 因其生物碱含量而具有显著的毒性风险,并有文献记载了因食用浆果而导致中毒的案例。 D PMID
  • 患者因残留生物碱的再吸收,在巴豆中毒后出现了晚发性抗胆碱能毒性反应。 D PMID

Frequently asked questions

What is Belladonna?

Belladonna (Atropa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Belladonna?

5 sourced findings are recorded for Belladonna; the strongest carries evidence grade D. For example: 该研究采用代谢工程来提高Atropa belladonna中羟基吗啉的产量和纯度,较野生型植物实现了6.511 mg/g DW 的增幅。

How strong is the evidence for Belladonna?

The strongest finding for Belladonna carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Belladonna safe? What are the side effects?

No major safety issues are recorded for Belladonna in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Belladonna interact with medications?

No drug interactions are recorded for Belladonna in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Belladonna?

Belladonna is also known as: Красавка (растение), Atrope.

Is Belladonna a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Acaricidal Activity and Potential Application of Atropa belladonna. literature abstract metadata
  2. T2 A Case of Belladonna Poisoning With Late-Onset Reappearance of Anticholinergic Toxicity. literature abstract metadata
  3. T2 A Pull-Block Metabolic Engineering Strategy for High-Yield and High-Purity Hyoscyamine Production in Atropa belladonna. literature abstract metadata
  4. T2 Toxic Risks of Nightshade Species: A comprehensive review of the documented toxicity of Atropa belladonna, Solanum dulcamara, and Solanum nigrum. literature abstract metadata
  5. T2 Unraveling the pleiotropic functions of Rhizobium rhizogenes rolB and rolC genes on phenotype, secondary metabolism, and drought tolerance in Atropa belladonna. literature abstract metadata