FolkKB

Khat

Catha edulis

Catha edulis，通常称为卡特或喀特，是一种在东非和阿拉伯半岛传统使用的植物。传统上，它用于社交聚会并能增强沟通技巧，但其具体医疗用途尚未得到充分记录。科学证据表明，长期咀嚼卡特可能与颞下颌关节紊乱、高血压、肝酶水平升高以及空腹血糖水平较高有关，尤其是使用频率越高。卡特使用者还显示出口腔白色病变的显著关联；然而，目前没有确凿证据将其与口腔或食道鳞状细胞癌联系起来。关于卡特使用的重大安全问题或药物相互作用尚未记录。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 荟萃分析表明长期嚼卡特草可能与颞下颌关节紊乱有关，但由于研究之间存在异质性，证据质量较低。 A PMID
  • 嚼卡特草的人患高血压的可能性是非使用者的2.4倍（比值比2.4，95%置信区间1.48-3.88）。 A PMID
  • 嚼卡特草的人在空腹血糖和转氨酶水平上高于不嚼者，且与剂量、使用时间和频率有关。 D PMID
  • 研究发现嚼食卡特（khat）与口腔白色病变之间存在显著的正相关，但未发现与口腔或食道鳞状细胞癌之间的明确关联。 A PMID
  • 研究发现，Catha edulis 在帕金森病模型中表现出神经保护活性，其他植物研究也是如此。 D PMID

Frequently asked questions

What is Khat?

Khat (Catha edulis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Khat?

5 sourced findings are recorded for Khat; the strongest carries evidence grade A. For example: 荟萃分析表明长期嚼卡特草可能与颞下颌关节紊乱有关，但由于研究之间存在异质性，证据质量较低。

How strong is the evidence for Khat?

The strongest finding for Khat carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Khat safe? What are the side effects?

No major safety issues are recorded for Khat in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Khat interact with medications?

No drug interactions are recorded for Khat in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Khat?

Khat is also known as: Кат.

Is Khat a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Does regular Khat (Catha edulis) chewing in adults increase the risk of hypertension compared to non-use? A systematic review and meta-analysis. literature abstract metadata
  2. T2 Khat chewing and its association with oral/esophageal squamous cell carcinoma and oral white lesions: A systematic review and meta-analysis. literature abstract metadata
  3. T2 Association between khat chewing and temporomandibular disorders: a systematic review and meta-analysis of observational studies. literature abstract metadata
  4. T2 Impact of chronic khat chewing on liver function tests and fasting blood glucose levels among adult male khat chewers. literature abstract metadata
  5. T2 The footprint of ethnopharmacology in drug discovery (ISE-APSS2024). literature abstract metadata