Asian Bittersweet
Celastrus orbiculatus
Celastrus orbiculatus，传统上未在任何已知医疗实践中使用，在科学研究中显示出前景。研究表明它可能通过干扰TGF-β/Smad途径抑制各种癌症中的癌干细胞增殖。此外，它还表现出抗菌活性，并且已经开发出优化的提取方法以提高植物根部中三萜类化合物的产量。另一项研究显示，pristimerin改善了小鼠胃黏膜损伤，而celafolin A-1减少了α-SMA和VEGF的表达，从而减小了激光诱导的脉络膜新生血管模型中的CNV区域。迄今为止，尚未记录Celastrus orbiculatus的重大安全问题或药物相互作用，但进一步的研究对于完全了解其潜在应用及其效果是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 细胞醇A-1降低了α-SMA和VEGF的表达，减少了CNV区域，并调节了Cryab磷酸化，在激光诱导的脉络膜新生血管小鼠模型中。
- Celastrus orbiculatus 在抑制各种癌症中的癌干细胞增殖方面显示出前景，尽管仍需进行更严格的临床试验。
- The study optimized an ultrasound-assisted extraction method for triterpenoids from Celastrus orbiculatus roots, achieving higher yields and significant antibacterial activity.
- Pristimerin 改善高剂量他莫昔芬诱导的SPEM小鼠胃黏膜损伤和oxyntic萎缩通过调节Cdkn1c介导的糖酵解重编程。
Frequently asked questions
What is Asian Bittersweet?
Asian Bittersweet (Celastrus orbiculatus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Asian Bittersweet?
4 sourced findings are recorded for Asian Bittersweet; the strongest carries evidence grade D. For example: 细胞醇A-1降低了α-SMA和VEGF的表达，减少了CNV区域，并调节了Cryab磷酸化，在激光诱导的脉络膜新生血管小鼠模型中。
How strong is the evidence for Asian Bittersweet?
The strongest finding for Asian Bittersweet carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Asian Bittersweet safe? What are the side effects?
No major safety issues are recorded for Asian Bittersweet in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Asian Bittersweet interact with medications?
No drug interactions are recorded for Asian Bittersweet in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Asian Bittersweet?
Asian Bittersweet is also known as: Древогубец круглолистный, Bourreau des arbres asiatique.
Is Asian Bittersweet a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Celafolin A-1 Ameliorates Subretinal Fibrosis via Inhibition of Crystallin Alpha B in a Laser-Induced Choroidal Neovascularization Mouse Model. literature abstract metadata
- T2 Cancer Stem Cells and Medicinal Plants, A Comprehensive Review of their Potential in Tumor Suppression and Recurrence Prevention. literature abstract metadata
- T2 Pristimerin ameliorates spasmolytic polypeptide-expressing metaplasia by modulating Cdkn1c (p57)-mediated glycolytic reprogramming. literature abstract metadata
- T2 Ultrasound-assisted supramolecular solvent extraction with enzymatic pretreatment of Celastrus orbiculatus roots: Process optimization, enrichment, and antibacterial activity. literature abstract metadata