Chinese goldthread
Coptis chinensis
中国黄连（Coptis chinensis），一种传统中药植物，常用于中医治疗各种疾病如湿热病症和炎症性疾病。然而，并没有特定的传统用途被记录在案。科学证据表明，其活性成分之一的去氢黄连碱可能通过靶向 CCL2、SPP1 和 ALB 抑制胃癌肝转移；但是需要进一步的实验验证来确认这些发现。此外，一项研究发现了 48 个 CcGRAS 基因在低光照条件下与 bZIP 蛋白表现出组织特异性共表达，可能有助于其治疗效果。该综述还强调了姜黄素和去氢黄连碱的多效药理特性，表明它们通过不同的机制在多种疾病中具有潜在的联合应用价值。迄今为止，并未记录 Coptis chinensis 有任何重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 共鉴定出48个CcGRAS基因，在光照压力与温度压力下表现出不同的表达模式，并在地下组织中观察到特定的共表达模式。
- 这项研究提示，黄连素可能通过靶向CCL2、SPP1和ALB抑制胃癌肝转移，但需要进一步的实验验证。
- 包括巴卡亭、小檗碱、姜黄素和异甘草素在内的中医复方可能减弱糖酵解并恢复预临床HCC中的免疫效应功能。
- 这篇综述评估了姜黄素和小檗碱在多种疾病中的复杂药理特性和治疗潜力，突出了它们的联合效应。
Frequently asked questions
What is Chinese goldthread?
Chinese goldthread (Coptis chinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese goldthread?
4 sourced findings are recorded for Chinese goldthread; the strongest carries evidence grade D. For example: 共鉴定出48个CcGRAS基因，在光照压力与温度压力下表现出不同的表达模式，并在地下组织中观察到特定的共表达模式。
How strong is the evidence for Chinese goldthread?
The strongest finding for Chinese goldthread carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese goldthread safe? What are the side effects?
No major safety issues are recorded for Chinese goldthread in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese goldthread interact with medications?
No drug interactions are recorded for Chinese goldthread in our sources. This does not rule them out — check with a pharmacist.
Is Chinese goldthread a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Emerging roles of combined curcumin and berberine in disease modulation: a comprehensive review of mechanisms and therapeutic relevance. literature abstract metadata
- T2 Traditional Chinese medicine reverses immune checkpoint resistance through lactate metabolic reprogramming in hepatocellular carcinoma: Mechanisms and therapeutic implications. literature abstract metadata
- T2 Genome-Wide Identification of the GRAS Transcription Factor Family in Coptis chinensis Reveals Tissue-Specific Co-Expression with bZIP Proteins Under Light Stress. literature abstract metadata
- T2 Exploring the Potential Molecular Mechanisms of Berberine against Gastric Cancer Liver Metastasis Based on Network Pharmacology and Bioinformatics. literature abstract metadata