Chinese goldthread
Coptis chinensis
草果（又称黄连）是一种传统中药植物，用于治疗消化系统疾病和炎症已有数百年历史。尽管其具体用途在西方传统中没有充分记录，但这种植物在中国传统医学（TCM）中被广泛使用了几个世纪。 科学研究表明，如黄酮类化合物等成分可能具有潜在的抗癌作用，通过抑制胃癌肝转移；然而这些发现需要进一步的实验验证。此外，研究表明，包括巴夏林、黄酮类化合物、姜黄素和异卡亭在内的传统中药成分可能会降低糖酵解并恢复预临床肝细胞癌（HCC）模型中的免疫效应功能。这些化合物的多效药理学特性正在被评估以确定其在各种疾病中的治疗潜力。 草果的安全性似乎是有利的，没有记录到重大问题。目前还没有报告与这种植物相关的药物相互作用，但进一步的研究是必要的，以便全面了解其安全性及有效性在临床环境中的表现。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 共鉴定出48个CcGRAS基因，在光照压力与温度压力下表现出不同的表达模式，并在地下组织中观察到特定的共表达模式。
- 这项研究提示，黄连素可能通过靶向CCL2、SPP1和ALB抑制胃癌肝转移，但需要进一步的实验验证。
- 包括巴卡亭、小檗碱、姜黄素和异甘草素在内的中医复方可能减弱糖酵解并恢复预临床HCC中的免疫效应功能。
- 这篇综述评估了姜黄素和小檗碱在多种疾病中的复杂药理特性和治疗潜力，突出了它们的联合效应。
Frequently asked questions
What is Chinese goldthread?
Chinese goldthread (Coptis chinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese goldthread?
4 sourced findings are recorded for Chinese goldthread; the strongest carries evidence grade D. For example: 共鉴定出48个CcGRAS基因，在光照压力与温度压力下表现出不同的表达模式，并在地下组织中观察到特定的共表达模式。
How strong is the evidence for Chinese goldthread?
The strongest finding for Chinese goldthread carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese goldthread safe? What are the side effects?
No major safety issues are recorded for Chinese goldthread in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese goldthread interact with medications?
No drug interactions are recorded for Chinese goldthread in our sources. This does not rule them out — check with a pharmacist.
Is Chinese goldthread a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Emerging roles of combined curcumin and berberine in disease modulation: a comprehensive review of mechanisms and therapeutic relevance. literature abstract metadata
- T2 Traditional Chinese medicine reverses immune checkpoint resistance through lactate metabolic reprogramming in hepatocellular carcinoma: Mechanisms and therapeutic implications. literature abstract metadata
- T2 Genome-Wide Identification of the GRAS Transcription Factor Family in Coptis chinensis Reveals Tissue-Specific Co-Expression with bZIP Proteins Under Light Stress. literature abstract metadata
- T2 Exploring the Potential Molecular Mechanisms of Berberine against Gastric Cancer Liver Metastasis Based on Network Pharmacology and Bioinformatics. literature abstract metadata