FolkKB

Yohimbe

Corynanthe johimbe

科里南坦·乔希姆贝是一种传统上在非洲各种医疗实践中使用的植物，尽管其具体用途尚未详细记录。科学研究表明，其提取物对神经活动表现出不同的影响，从轻微抑制到过度兴奋，并且不同样本之间的效力有所不同。研究还指出，在全球生物多样性信息设施（GBIF）数据库中，含有生物碱的这种植物种类平均出现频率更高，通常与栽培实践有关，而与其他非药用品种相比则较低。此外，已对参与单萜吲哚生物碱生物合成的酶进行了表征，并概述了一系列体外试验来评估其神经毒性潜力，使用了大鼠皮层原代神经元、斑马鱼胚胎和C. elegans。迄今为止尚未记录到科里南坦·乔希姆贝的重大安全问题或已知药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 含有生物碱的药用植物种类在GBIF中的平均出现频率较高，通常与栽培有关，而非性质的植物则不然。 D PMID
  • 研究发现，各种植物提取物对体外神经活动有不同的影响，从轻微抑制到过度兴奋不等。 D PMID
  • 该研究鉴定并表征了HYC3O和HYC3R酶，这些酶在多种植物物种中的单萜吲哚生物碱中反转C3立体化学。 D PMID
  • 该研究概述了一系列体外试验，用于评估植物的神经毒性潜力，包括初级大鼠皮层神经元、斑马鱼胚胎和C. elegans。 D PMID

Frequently asked questions

What is Yohimbe?

Yohimbe (Corynanthe johimbe) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Yohimbe?

4 sourced findings are recorded for Yohimbe; the strongest carries evidence grade D. For example: 含有生物碱的药用植物种类在GBIF中的平均出现频率较高，通常与栽培有关，而非性质的植物则不然。

How strong is the evidence for Yohimbe?

The strongest finding for Yohimbe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Yohimbe safe? What are the side effects?

No major safety issues are recorded for Yohimbe in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Yohimbe interact with medications?

No drug interactions are recorded for Yohimbe in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Yohimbe?

Yohimbe is also known as: Йохимбе, Yohimbé.

Is Yohimbe a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity-An Update and Forward Look. literature abstract metadata
  2. T2 Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety. literature abstract metadata
  3. T2 Dose-response assessment of neuroactive botanical extracts and their bioactive constituents using microelectrode array (MEA) recordings in rat primary cortical cultures. literature abstract metadata
  4. T2 Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. literature abstract metadata