FolkKB

Yohimbe

Corynanthe johimbe

科里南特·乔希姆贝是一种含有生物碱的药用植物，传统上在某些非洲草药疗法中用于多种目的，但其具体用途尚未充分记录。科学证据表明，该物种的植物提取物在体外对神经活动表现出不同的影响，一些显示出轻微抑制作用，而另一些则表现出过度兴奋。研究还识别了参与不同植物物种中单萜吲哚生物碱化学转化的酶HYC3O和HYC3R，突显了其生物学活性的潜在机制。迄今为止，科里南特·乔希姆贝没有记录到重大安全问题或已知药物相互作用，但进一步研究对于全面了解其效果及其应用是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 含有生物碱的药用植物种类在GBIF中的平均出现频率较高，通常与栽培有关，而非性质的植物则不然。 D PMID
  • 研究发现，各种植物提取物对体外神经活动有不同的影响，从轻微抑制到过度兴奋不等。 D PMID
  • 该研究鉴定并表征了HYC3O和HYC3R酶，这些酶在多种植物物种中的单萜吲哚生物碱中反转C3立体化学。 D PMID
  • 该研究概述了一系列体外试验，用于评估植物的神经毒性潜力，包括初级大鼠皮层神经元、斑马鱼胚胎和C. elegans。 D PMID

Frequently asked questions

What is Yohimbe?

Yohimbe (Corynanthe johimbe) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Yohimbe?

4 sourced findings are recorded for Yohimbe; the strongest carries evidence grade D. For example: 含有生物碱的药用植物种类在GBIF中的平均出现频率较高，通常与栽培有关，而非性质的植物则不然。

How strong is the evidence for Yohimbe?

The strongest finding for Yohimbe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Yohimbe safe? What are the side effects?

No major safety issues are recorded for Yohimbe in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Yohimbe interact with medications?

No drug interactions are recorded for Yohimbe in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Yohimbe?

Yohimbe is also known as: Йохимбе, Yohimbé.

Is Yohimbe a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity-An Update and Forward Look. literature abstract metadata
  2. T2 Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety. literature abstract metadata
  3. T2 Dose-response assessment of neuroactive botanical extracts and their bioactive constituents using microelectrode array (MEA) recordings in rat primary cortical cultures. literature abstract metadata
  4. T2 Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. literature abstract metadata