Calabash Tree

Crescentia cujete

Crescentia cujete, also known as calabash tree or gour, is a plant native to tropical regions of Central and South America. While traditional uses for this plant are not well-documented, it has been studied in various contexts. Scientific evidence suggests that fermented Crescentia cujete may have some potential immunomodulatory effects, particularly by increasing CD4+ and CD4+/CD8+ ratios. In another study involving ranchu goldfish, the fruit extract of Crescentia cujete showed significant increases in heterophils and affected C-reactive protein levels, COX-2 immunoreactivity, and CD4+ levels. Additionally, molecular docking and dynamics simulations have identified several compounds with potential antidiabetic activity, though further validation is required to confirm these findings. When combined with enrofloxacin, Crescentia cujete showed improved radiological and immunological outcomes in rat models of pneumonic pasteurellosis, although its effect on CD8+ immune expression was not significant. No major safety issues or recorded drug interactions have been identified for this plant.

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究发现发酵的Crescentia cujete 对大多数血液学和临床化学参数没有显著影响,但增加了CD4+ 和CD4+/CD8+ 比值。 D PMID
  • Crescentia cujete 果提取物显著增加了中性粒细胞并影响了 Ranchu 鲟鱼的 C 反应蛋白、COX-2 免疫活性和 CD4+ 水平。 D PMID
  • 研究发现,来自角果属树(Crescentia cujete)的几种化合物具有潜在的抗糖尿病活性,可针对与2型糖尿病相关的关键酶,但需要进一步验证。 D PMID
  • FCC与恩诺沙星联合使用时,在诱导肺炎巴氏杆菌感染的大鼠中显示出更好的肺修复和免疫表达增加,与其他治疗方法相比,但并未影响CD8+免疫表达。 D PMID

Frequently asked questions

What is Calabash Tree?

Calabash Tree (Crescentia cujete) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Calabash Tree?

4 sourced findings are recorded for Calabash Tree; the strongest carries evidence grade D. For example: 研究发现发酵的Crescentia cujete 对大多数血液学和临床化学参数没有显著影响,但增加了CD4+ 和CD4+/CD8+ 比值。

How strong is the evidence for Calabash Tree?

The strongest finding for Calabash Tree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Calabash Tree safe? What are the side effects?

No major safety issues are recorded for Calabash Tree in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Calabash Tree interact with medications?

No drug interactions are recorded for Calabash Tree in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Calabash Tree?

Calabash Tree is also known as: Калебасовое дерево, calebassier.

Is Calabash Tree a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Cheminformatics identification of modulators of key carbohydrate-metabolizing enzymes from C. cujete for type-2 diabetes mellitus intervention. literature abstract metadata
  2. T2 Effects of fermented Crescentia cujete L. on the profile of hematology, clinical chemistry, and circulatory CD4+/CD8+ in Sprague Dawley rats. literature abstract metadata
  3. T2 Effects of Crescentia cujete (L.) fruit extract on the profile of hematology of ranchu goldfish (Carassius auratus). literature abstract metadata
  4. T2 The standardization and efficacy of fermented Crescentia cujete (L.) in combination with enrofloxacin against artificially induced pneumonic pasteurellosis in rat models. literature abstract metadata