FolkKB

Chinese-quinine

Dichroa febrifuga

二飞藤是一种传统中药。尽管其具体用途在传统实践中没有很好地记录，但在现代科学研究中显示出前景。研究表明，从二飞藤中提取的抑制剂卤佛吉诺（halofuginone）可以减少小鼠大脑硬膜厚度和腰椎纤维化程度，这可能表明治疗某些神经系统疾病的潜力。此外，卤佛吉诺显著抑制结肠癌细胞生长，而另一种化合物FFG已被证明通过调节IGF1R-PI3K/AKT凋亡轴来限制猪流行性腹泻病毒（PEDV）的复制。在感染Eimeria tenella的小鸡中进行的一项研究显示，二飞藤叶提取物（DFL）治疗改善了生长性能、减少了卵囊排出并保护了肠屏障完整性。从安全角度来看，没有记录到重大问题，并且目前没有已知与二飞藤或其衍生物相关的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • FFG通过调节PI3K/AKT-凋亡途径来限制PEDV的复制。 D PMID
  • Halofuginone reduced dura mater thickness and epidural fibrosis grades in a rat craniectomy model. D PMID
  • 卤苯酮，源自 Dichroa febrifuga 的抑制剂，与硼替佐米协同显著抑制结肠癌细胞的生长。 D PMID
  • DFL治疗显著改善了生长性能，减少了孢子释放，并保护了感染E. tenella鸡的肠屏障完整性。 D PMID

Frequently asked questions

What is Chinese-quinine?

Chinese-quinine (Dichroa febrifuga) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Chinese-quinine?

4 sourced findings are recorded for Chinese-quinine; the strongest carries evidence grade D. For example: FFG通过调节PI3K/AKT-凋亡途径来限制PEDV的复制。

How strong is the evidence for Chinese-quinine?

The strongest finding for Chinese-quinine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Chinese-quinine safe? What are the side effects?

No major safety issues are recorded for Chinese-quinine in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Chinese-quinine interact with medications?

No drug interactions are recorded for Chinese-quinine in our sources. This does not rule them out — check with a pharmacist.

Is Chinese-quinine a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 The glutamyl-prolyl-tRNA synthetase 1 inhibitor halofuginone exerts synergistic antitumor effects with bortezomib in colon cancer cells. literature abstract metadata
  2. T2 Antifibrotic and anti-inflammatory properties of halofuginone in a rat craniectomy model. literature abstract metadata
  3. T2 Study on the therapeutic potential of Dichroa febrifuga Lour. as a novel natural anticoccidial agent for Eimeria tenella infection in chicks. literature abstract metadata
  4. T2 Febrifugine dihydrochloride restricts porcine epidemic diarrhea virus replication by modulating the IGF1R-driven PI3K/AKT-apoptosis axis. literature abstract metadata