FolkKB

Elephant's Foot

Elephantopus scaber

Elephantopus scaber 是一种传统上在亚洲和非洲的各种民间医学实践中使用的植物。尽管其具体的传统用途没有很好地记录，但研究表明它含有潜在的抗癌、抗炎和器官保护活性的次级代谢物，通过多种信号通路起作用。研究指出，对抗有丝分裂提取物存在基因型特异性反应，表明有效性的差异取决于植物的遗传组成。值得注意的是，去氧象牙喙实蝇素能够抑制IL-2的产生，通过抑制NF-κB和钙调蛋白/NFAT信号通路。此外，在Elephantopus scaber 和 Elephantopus tomentosus中，不同的次级代谢物显示出对肝细胞癌的不同抗性活性。安全性数据未显示重大问题，并且根据当前的研究资料没有记录到任何药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 象豆（Elephantopus scaber）含有多种次生代谢物，通过多种信号途径显示出显著的抗癌、抗炎和器官保护作用。 D PMID
  • 研究发现，抗有丝分裂提取物对不同基因型表现出剂量依赖性反应，而G. superba 显示出提高水稻产量特性的潜力。 D PMID
  • 去氧象牙皂苷通过抑制NF-κB和calcineurin/NFAT信号通路抑制了T细胞中的IL-2产生。 D PMID
  • 这项研究在Elephantopus scaber和Elephantopus tomentosus中鉴定了不同的次级代谢物，显示出不同的抗肝细胞癌活性。 D PMID

Frequently asked questions

What is Elephant's Foot?

Elephant's Foot (Elephantopus scaber) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Elephant's Foot?

4 sourced findings are recorded for Elephant's Foot; the strongest carries evidence grade D. For example: 象豆（Elephantopus scaber）含有多种次生代谢物，通过多种信号途径显示出显著的抗癌、抗炎和器官保护作用。

How strong is the evidence for Elephant's Foot?

The strongest finding for Elephant's Foot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Elephant's Foot safe? What are the side effects?

No major safety issues are recorded for Elephant's Foot in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Elephant's Foot interact with medications?

No drug interactions are recorded for Elephant's Foot in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Elephant's Foot?

Elephant's Foot is also known as: Элефантопус шершавый.

Is Elephant's Foot a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Untargeted metabolomics and in-house database analysis reveal differences between Elephantopus scaber L. and Elephantopus tomentosus L. literature abstract metadata
  2. T2 Elephantopus scaber L.: phytochemistry, pharmacology, nanoformulation, and synthetic modification - a review. literature abstract metadata
  3. T2 Deoxyelephantopin, a natural sesquiterpene lactone, suppresses IL-2 production of ConA-activated T lymphocytes through inhibiting NF-κB and calcineurin/NFAT signaling. literature abstract metadata
  4. T2 Agronomic responses of rice to putative polyploid-inducing plant extracts: a screening study. literature abstract metadata