FolkKB

false black pepper

Embelia ribes

埃姆贝利娅·里比斯是一种传统植物，主要用于阿育吠陀医学。其特定应用尚未充分记录，但各种科学研究表明它具有潜力。研究表明，来自埃姆贝利娅·里比斯的5-О-甲基埃姆贝尔林可以通过破坏ACO1-TPI1相互作用诱导透明细胞肾细胞癌细胞发生铁死亡，这可能暗示抗癌性质。此外，表观遗传调节剂AZ和SB已被观察到改变埃姆贝利娅·里比斯内生菌的代谢物谱型，从而增强某些具有潜在抗癌和抗菌活性化合物的体内生产。值得注意的是，在毒理学研究中，含有埃姆贝利娅·里比斯（NPF）的配方显示出显著的抗糖尿病效果且无不良副作用。尚未发现该植物的重大安全问题或记录在案的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 5-氧甲基埃姆贝林通过破坏ACO1-TPI1相互作用诱导透明细胞肾癌的铁死亡。 D PMID
  • 表观修饰剂AZ和SB改变了来自Embelia ribes内生菌的代谢物谱型，激活了沉默的代谢物并增强了某些化合物的产生。 D PMID
  • 该研究合成了来自Embelia ribes果实的embelin-Sn复合物，并在体外显示出潜在的抗癌和抗菌活性。 D PMID
  • NPF，含有Embelia ribes等其他草药，显示出显著的抗糖尿病潜力且在毒理学研究中无不良反应。 D PMID

Frequently asked questions

What is false black pepper?

false black pepper (Embelia ribes) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about false black pepper?

4 sourced findings are recorded for false black pepper; the strongest carries evidence grade D. For example: 5-氧甲基埃姆贝林通过破坏ACO1-TPI1相互作用诱导透明细胞肾癌的铁死亡。

How strong is the evidence for false black pepper?

The strongest finding for false black pepper carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is false black pepper safe? What are the side effects?

No major safety issues are recorded for false black pepper in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does false black pepper interact with medications?

No drug interactions are recorded for false black pepper in our sources. This does not rule them out — check with a pharmacist.

Is false black pepper a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Therapeutic potential of novel tin metal complex of embelin isolated from Embelia ribes fruits. literature abstract metadata
  2. T2 Pharmacokinetic, toxicological, and antidiabetic evaluation of a novel polyherbal formulation. literature abstract metadata
  3. T2 Effect of epigenetic modulation on metabolites from endophytes isolated from Embelia ribes. literature abstract metadata
  4. T2 5-O-Methylembelin disrupts the ACO1-TPI1 interaction to promote ferroptosis in clear cell renal cell carcinoma. literature abstract metadata