Chinese Ephedra
Ephedra sinica
Ephedra sinica 在传统中医中被使用，已在多种科学研究中显示出潜力。尽管具体的传统用途没有很好地记录下来，但其在管理与类风湿性关节炎（RA）和肝损伤相关的症状方面具有潜在益处，通过肠道微生物群的调节以及多个生物过程分别实现。科学证据表明，某些从 Ephedra sinica 中提取的化合物可能具有治疗效果，但在不同研究中的结果存在差异。值得注意的是，一种源自植物的多成分药针配方在调节与肝损伤相关的炎症和线粒体质量控制方面显示出潜力。此外，含有 Ephedra sinica 成分的吴头汤在缺氧条件下通过靶向 Notch 信号通路显著抑制了成纤维细胞样滑膜细胞的侵袭。从 Ephedra sinica 中提取的化合物 IMPHY004834（Mahuannin D）已作为调节与 PD-1 相互作用的潜在先导物出现，但需要进一步研究来确认这些发现。迄今为止尚未记录任何重大安全问题或药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自麻黄的TCMP在动物模型中通过调节肠道微生物群显著缓解了RA症状，但不同研究的结果存在异质性。
- 多组分药针制剂在调节与肝损伤相关的多个生物过程方面显示出潜力，包括炎症和线粒体质量控制。
- 乌头汤显著抑制了由缺氧诱导的纤维样滑膜细胞侵袭表型，通过靶向Notch信号通路在体内外模型中均有效。
- Ephedra sinica 的IMPHY004834（马胡安宁D）作为一种与PD-1具有稳定相互作用的潜在先导化合物出现。
Frequently asked questions
What is Chinese Ephedra?
Chinese Ephedra (Ephedra sinica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese Ephedra?
4 sourced findings are recorded for Chinese Ephedra; the strongest carries evidence grade A. For example: 来自麻黄的TCMP在动物模型中通过调节肠道微生物群显著缓解了RA症状，但不同研究的结果存在异质性。
How strong is the evidence for Chinese Ephedra?
The strongest finding for Chinese Ephedra carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese Ephedra safe? What are the side effects?
No major safety issues are recorded for Chinese Ephedra in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese Ephedra interact with medications?
No drug interactions are recorded for Chinese Ephedra in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese Ephedra?
Chinese Ephedra is also known as: Хвойник китайский.
Is Chinese Ephedra a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 In search of novel PD1 inhibitor from natural products by high-throughput virtual screening and molecular dynamics simulation. literature abstract metadata
- T2 Effects of traditional Chinese medicine polysaccharides on rheumatoid arthritis through gut microbiota modulation: a systematic review in animal models. literature abstract metadata
- T2 Wutou decoction ameliorates rheumatoid arthritis through inhibiting hypoxia-induced invasive phenotype of fibroblast-like synoviocytes mediated by the Notch pathway. literature abstract metadata
- T2 Network Pharmacology Analysis Reveals Multi-Target Hepatoprotective Mechanisms of a Multi-Component Pharmacopuncture Against Ephedra-Associated Liver Injury with Implications for Mitochondrial Quality Control. literature abstract metadata