Korean barrenwort

Epimedium koreanum

玉皮豆,一种起源于东亚的传统草药,在各种文化实践中被使用,但这种植物的具体传统用途尚未详细记录。科学研究已经确定,玉皮豆含有多种药理活性化合物,支持其某些潜在应用的同时也突显了可能的毒性问题。例如,野生玉皮豆Nakai已被证明通过激活SIRT1/NRF2/PPARγ信号通路提供对有机锡诱导的肾损伤和糖尿病性肾病的优越保护作用。此外,该植物物种中的内生真菌Colletotrichum endophyticum(Y8)已显示出促进阿拉伯芥生长的能力,通过增加根长和侧根数量。此外,玉皮豆(EKB)对多发性骨髓瘤细胞表现出强大的细胞毒性,通过稳定关键致癌基因的关键G4结构。尚未发现该植物的重大安全问题或记录的药物相互作用,尽管进一步的研究对于完全了解其潜在益处和风险是必要的。

速览
最佳证据
A
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究发现,淫羊藿含有多种具有多种药理作用的化合物,支持一些传统用途,但突显潜在毒性问题。 A PMID
  • 森林栽培的Epimedium koreanum Nakai通过激活SIRT1/NRF2/PPARγ信号通路,提供对由有机锡诱导的肾损伤和糖尿病性肾病的优越保护。 D PMID
  • 来自韩国玉竹Epimedium Nakai的内生真菌Colletotrichum endophyticum (Y8)通过增加根长和侧根数量促进了阿拉伯芥Arabidopsis thaliana的生长。 D PMID
  • EKB 对多发性骨髓瘤细胞表现出强大的细胞毒性,通过稳定关键致癌基因的G4 结构。 D PMID
  • 来自朝鲜淫羊藿的 EKPA 在糖尿病大鼠中显示出剂量依赖性的肝功能和血液参数改善。 D PMID

Frequently asked questions

What is Korean barrenwort?

Korean barrenwort (Epimedium koreanum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Korean barrenwort?

5 sourced findings are recorded for Korean barrenwort; the strongest carries evidence grade A. For example: 研究发现,淫羊藿含有多种具有多种药理作用的化合物,支持一些传统用途,但突显潜在毒性问题。

How strong is the evidence for Korean barrenwort?

The strongest finding for Korean barrenwort carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Korean barrenwort safe? What are the side effects?

No major safety issues are recorded for Korean barrenwort in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Korean barrenwort interact with medications?

No drug interactions are recorded for Korean barrenwort in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Korean barrenwort?

Korean barrenwort is also known as: Эпимедиум корейский.

Is Korean barrenwort a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 A systematic review of traditional uses, phytochemistry, pharmacology and toxicity of Epimedium koreanum Nakai. literature abstract metadata
  2. T2 Directly targeting G-quadruplexes contributes to the anti-multiple myeloma efficacy of Epimedokoreanin B. literature abstract metadata
  3. T2 Structure analysis of an acidic polysaccharide isolated from Epimedium koreanum Nakai and its improvement on liver oxidative stress injury in STZ-induced diabetic rats via NRF2/HO-1 pathways. literature abstract metadata
  4. T2 The endogenous fungus Colletotrichum endophyticum from Korean epimedium Nakai promoted the growth of the model plant Arabidopsis thaliana. literature abstract metadata
  5. T2 Forest-cultivated Epimedium koreanum Nakai mitigates organotin-induced renal injury and the exacerbation of diabetic nephropathy via the SIRT1/NRF2/PPARγ signaling pathways. literature abstract metadata