Ferula assa-foetida
Ferula assa-foetida
艾苏夫特拉（Ferula assa-foetida），一种传统植物，主要用于其油树脂在烹饪和民间医学实践中的应用，特别是在伊朗和阿富汗。尽管没有具体的传统用途记录，现代科学研究表明，这种植物的羟基肉桂酸能够抑制cGAS-STING信号通路，从而减少2型糖尿病模型中的炎症和脂肪变性。此外，研究表明艾苏夫特拉对结肠癌细胞具有剂量依赖性的细胞毒性作用，通过下调PD-L1表达。该植物的生物活性成分在特定UV-C照射条件和温度下也会积累在愈伤组织培养中，表明有可能优化其栽培。没有记录到主要的安全问题或已知药物相互作用，但进一步研究对于完全了解其治疗应用及其潜在副作用是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从Ferula assa-foetida中提取的羟基桂皮酸通过与COPII Sec24 B位点结合抑制cGAS-STING信号传导，减少T2DM模型中的炎症和脂肪变性。
- 该研究开发了用于 Ferula asa-foetida 的体外再生系统，并发现卷积神经网络在预测最佳植物生长调节剂方面取得了最高精度（87%）。
- 乳香树（Ferula assa-foetida）油树脂在结肠癌HCT-116细胞中表现出剂量依赖性细胞毒性并下调了PD-L1的表达。
- UV-C照射与温度结合影响Ferula assa-foetida愈伤组织培养中活性化合物的积累。
Frequently asked questions
What is Ferula assa-foetida?
Ferula assa-foetida (Ferula assa-foetida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ferula assa-foetida?
4 sourced findings are recorded for Ferula assa-foetida; the strongest carries evidence grade D. For example: 从Ferula assa-foetida中提取的羟基桂皮酸通过与COPII Sec24 B位点结合抑制cGAS-STING信号传导，减少T2DM模型中的炎症和脂肪变性。
How strong is the evidence for Ferula assa-foetida?
The strongest finding for Ferula assa-foetida carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Ferula assa-foetida safe? What are the side effects?
No major safety issues are recorded for Ferula assa-foetida in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ferula assa-foetida interact with medications?
No drug interactions are recorded for Ferula assa-foetida in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Ferula assa-foetida?
Ferula assa-foetida is also known as: ферула вонючая.
Is Ferula assa-foetida a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Deep Learning and Machine Learning Modeling Identifies Thidiazuron as a Key Modulator of Somatic Embryogenesis and Shoot Organogenesis in Ferula assa-foetida L. literature abstract metadata
- T2 UV-C mediated regulation of key biosynthetic genes for higher accumulation of pharmacologically significant bioactive secondary metabolites in friable callus cultures of Ferula assa-foetida. literature abstract metadata
- T2 Exploring the Therapeutic Potential of Ferula assa-foetida Oleo-gum-resin in Colon Cancer: Emerging Links to Immunotherapy. literature abstract metadata
- T2 Hydroxycinnamic acids target COPII cargo sorting machinery to attenuate inflammation via the cGAS-STING axis. literature abstract metadata