Ferula assa-foetida
Ferula assa-foetida
Ferula asafoetida，又称作asafoetida，是一种传统的植物，原产于伊朗和阿富汗。传统上，它因其辛辣的气味和强烈的风味而在烹饪应用中被使用，但历史上没有记录其特定的药用用途。 科学研究表明，Ferula asafoetida中的羟基肉桂酸可以与COPII的Sec24 B-位点结合，抑制cGAS-STING信号传导，从而可能减少2型糖尿病模型中的炎症和脂肪变性。此外，开发了一种体外再生系统，并发现卷积神经网络在预测最佳生长调节剂方面达到了87%的准确性，这表明有可能改进栽培技术。Ferula asafoetida的油树脂对HCT-116结肠癌细胞表现出剂量依赖性的细胞毒性，并下调了PD-L1表达。此外，UV-C照射与温度结合影响了愈伤组织培养中生物活性化合物的积累。 目前Ferula asafoetida的安全性问题很小；尚未记录重大问题。然而，任何基于植物的物质都可能因个体差异而产生不同的反应。目前也没有报告过其与药物之间存在显著相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从Ferula assa-foetida中提取的羟基桂皮酸通过与COPII Sec24 B位点结合抑制cGAS-STING信号传导，减少T2DM模型中的炎症和脂肪变性。
- 该研究开发了用于 Ferula asa-foetida 的体外再生系统，并发现卷积神经网络在预测最佳植物生长调节剂方面取得了最高精度（87%）。
- 乳香树（Ferula assa-foetida）油树脂在结肠癌HCT-116细胞中表现出剂量依赖性细胞毒性并下调了PD-L1的表达。
- UV-C照射与温度结合影响Ferula assa-foetida愈伤组织培养中活性化合物的积累。
Frequently asked questions
What is Ferula assa-foetida?
Ferula assa-foetida (Ferula assa-foetida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ferula assa-foetida?
4 sourced findings are recorded for Ferula assa-foetida; the strongest carries evidence grade D. For example: 从Ferula assa-foetida中提取的羟基桂皮酸通过与COPII Sec24 B位点结合抑制cGAS-STING信号传导，减少T2DM模型中的炎症和脂肪变性。
How strong is the evidence for Ferula assa-foetida?
The strongest finding for Ferula assa-foetida carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Ferula assa-foetida safe? What are the side effects?
No major safety issues are recorded for Ferula assa-foetida in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ferula assa-foetida interact with medications?
No drug interactions are recorded for Ferula assa-foetida in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Ferula assa-foetida?
Ferula assa-foetida is also known as: ферула вонючая.
Is Ferula assa-foetida a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Deep Learning and Machine Learning Modeling Identifies Thidiazuron as a Key Modulator of Somatic Embryogenesis and Shoot Organogenesis in Ferula assa-foetida L. literature abstract metadata
- T2 UV-C mediated regulation of key biosynthetic genes for higher accumulation of pharmacologically significant bioactive secondary metabolites in friable callus cultures of Ferula assa-foetida. literature abstract metadata
- T2 Exploring the Therapeutic Potential of Ferula assa-foetida Oleo-gum-resin in Colon Cancer: Emerging Links to Immunotherapy. literature abstract metadata
- T2 Hydroxycinnamic acids target COPII cargo sorting machinery to attenuate inflammation via the cGAS-STING axis. literature abstract metadata