FolkKB

Suffrutescent securinega

Flueggea suffruticosa

Flueggea suffruticosa，一种传统上没有记录用途的植物，在科学研究中显示出潜力。研究表明，securinine 是该植物中的一种生物碱，可杀死人类癌细胞并调节多条信号通路，提示其可能具有抗肿瘤特性；然而，需要进一步研究以确认这些发现。4,5‑dehydro‑6‑oxoallosecurinine 的衍生物激活了 Keap1-Nrf2 通路，诱导抗氧化基因表达并降低小胶质细胞的炎症。此外，通过发现和合成方法从 Flueggea suffruticosa 中鉴定出四种新的 Securinega 生物碱。SEC 治疗通过增加肿瘤负荷小鼠中 CD8⁺ T 细胞的活化，增强了抗肿瘤免疫力。目前尚未发现主要安全问题或已记录的药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 二萜碱可以杀死多种人类癌细胞并调节多个信号通路，显示出作为抗癌剂的潜力，尽管还需要更多的研究。 A PMID
  • 4,5-脱氢-6-氧代阿尔洛糖曲辛的衍生物激活了Keap1-Nrf2途径，诱导抗氧化基因表达并减少小胶质细胞炎症。 D PMID
  • 研究在通过发现和合成方法对Flueggea suffruticosa进行研究时，发现了四种新的Securinega生物碱。 D PMID
  • SEC治疗通过增加肿瘤小鼠中CD8⁺ T细胞的激活来增强抗肿瘤免疫。 D PMID

Frequently asked questions

What is Suffrutescent securinega?

Suffrutescent securinega (Flueggea suffruticosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Suffrutescent securinega?

4 sourced findings are recorded for Suffrutescent securinega; the strongest carries evidence grade A. For example: 二萜碱可以杀死多种人类癌细胞并调节多个信号通路，显示出作为抗癌剂的潜力，尽管还需要更多的研究。

How strong is the evidence for Suffrutescent securinega?

The strongest finding for Suffrutescent securinega carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Suffrutescent securinega safe? What are the side effects?

No major safety issues are recorded for Suffrutescent securinega in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Suffrutescent securinega interact with medications?

No drug interactions are recorded for Suffrutescent securinega in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Suffrutescent securinega?

Suffrutescent securinega is also known as: Секуринега полукустарниковая, fluguéa d'Orient.

Is Suffrutescent securinega a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Potential anticancer activities of securinine and its molecular targets. literature abstract metadata
  2. T2 Securinine bolsters anti-tumor immunity by promoting CD8⁺ T cell activation. literature abstract metadata
  3. T2 Allosecurinine Derivative with Two Michael Acceptors Activates Keap1-Nrf2 Pathway. literature abstract metadata
  4. T2 Discovery and synthesis of flueggeacosines D-F and securingine J. literature abstract metadata