Suffrutescent securinega
Flueggea suffruticosa
Flueggea suffruticosa is a plant traditionally used in some Asian herbal practices, particularly in China. It has been utilized for various ailments but specific traditional uses are not well-documented. Scientific research has identified four new Securinega alkaloids from this plant and shown that SEC treatment can enhance anti-tumor immunity by increasing CD8⁺ T cell activation in tumor-bearing mice models. Additionally, securinine, a compound derived from the plant, demonstrates potential as an anticancer agent by killing human cancer cells and regulating multiple signal pathways; however, more in vivo and clinical studies are required to confirm these findings. No major safety issues or recorded drug interactions have been noted for Flueggea suffruticosa thus far.
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 二萜碱可以杀死多种人类癌细胞并调节多个信号通路，显示出作为抗癌剂的潜力，尽管还需要更多的研究。
- A derivative of 4,5-dehydro-6-oxoallosecurinine activated the Keap1-Nrf2 pathway, inducing antioxidant gene expression and reducing inflammation in microglia.
- 研究在通过发现和合成方法对Flueggea suffruticosa进行研究时，发现了四种新的Securinega生物碱。
- SEC治疗通过增加肿瘤小鼠中CD8⁺ T细胞的激活来增强抗肿瘤免疫。
Frequently asked questions
What is Suffrutescent securinega?
Suffrutescent securinega (Flueggea suffruticosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Suffrutescent securinega?
4 sourced findings are recorded for Suffrutescent securinega; the strongest carries evidence grade A. For example: 二萜碱可以杀死多种人类癌细胞并调节多个信号通路，显示出作为抗癌剂的潜力，尽管还需要更多的研究。
How strong is the evidence for Suffrutescent securinega?
The strongest finding for Suffrutescent securinega carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Suffrutescent securinega safe? What are the side effects?
No major safety issues are recorded for Suffrutescent securinega in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Suffrutescent securinega interact with medications?
No drug interactions are recorded for Suffrutescent securinega in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Suffrutescent securinega?
Suffrutescent securinega is also known as: Секуринега полукустарниковая, fluguéa d'Orient.
Is Suffrutescent securinega a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Potential anticancer activities of securinine and its molecular targets. literature abstract metadata
- T2 Securinine bolsters anti-tumor immunity by promoting CD8⁺ T cell activation. literature abstract metadata
- T2 Allosecurinine Derivative with Two Michael Acceptors Activates Keap1-Nrf2 Pathway. literature abstract metadata
- T2 Discovery and synthesis of flueggeacosines D-F and securingine J. literature abstract metadata