Cascara buckthorn
Frangula purshiana
弗朗古拉·普尔希亚（Oregon葡萄），是一种传统植物，被原住民社区使用。尽管其在传统医学中的具体用途尚未详细记录，但在加拿大不列颠哥伦比亚省的宠物治疗中，它已被用于驱虫和胃部问题。科学研究表明，弗朗古拉·普尔希亚可以通过hPXR激活在HepG2细胞中显著增加CYP3A4 mRNA基因表达，这表明其潜在药理活性。然而，更广泛的科学证据有限，需要进一步研究来确认这些发现。对于这种植物没有报告过重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Frangula purshiana 显著增加了CYP3A4 mRNA基因表达，可能是通过在HepG2细胞中激活hPXR实现的。
- 弗朗古拉·普尔西安娜在加拿大不列颠哥伦比亚州的植物疗法中用于治疗宠物。
- 光镜和电子显微镜观察显示了弗朗吉拉·阿佐里卡树皮的特征结构，有助于其鉴定。
- 弗朗古拉·普尔希亚纳被用作驱虫剂与其他植物一起治疗宠物体内外寄生虫和胃部问题于加拿大不列颠哥伦比亚省。
Frequently asked questions
What is Cascara buckthorn?
Cascara buckthorn (Frangula purshiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cascara buckthorn?
4 sourced findings are recorded for Cascara buckthorn; the strongest carries evidence grade D. For example: Frangula purshiana 显著增加了CYP3A4 mRNA基因表达，可能是通过在HepG2细胞中激活hPXR实现的。
How strong is the evidence for Cascara buckthorn?
The strongest finding for Cascara buckthorn carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cascara buckthorn safe? What are the side effects?
No major safety issues are recorded for Cascara buckthorn in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cascara buckthorn interact with medications?
No drug interactions are recorded for Cascara buckthorn in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cascara buckthorn?
Cascara buckthorn is also known as: Каскара, cascara.
Is Cascara buckthorn a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada. literature abstract metadata
- T2 Contribution of Light and Electron Microscopy to Identification of Bark from Frangula azorica, an Azorean Medicinal Plant. literature abstract metadata
- T2 Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care? literature abstract metadata
- T2 In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity. literature abstract metadata