FolkKB

ginkgo

Ginkgo biloba

银杏叶是一种起源于东亚的传统植物，特别用于认知和循环支持。它在中国医学中被传统上使用了几个世纪。科学研究表明，银杏叶提取物可能通过多种机制具有潜在的神经保护作用，包括银杏生物碱B和槲皮素对补体蛋白的调节。然而，临床数据仍然不足以证明其常规应用。尚未记录任何重大安全问题；但是，值得注意的是，银杏叶可能会增强抗凝血或抗血小板药物引起的出血风险，因为可能存在增加血液稀释作用的叠加效应。

速览
传统用于
认知和循环支持（传统）
传统体系
西方植物疗法
最佳证据
A
注意事项
⚕ 1

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

传统用途

科学怎么说

  • 研究显示，银杏叶提取物中的银杏内酯B和槲皮素可能作为天然的补体调节剂通过稳定与C3和C5蛋白的相互作用。 D PMID
  • GA 在分化过程中通过抑制凋亡提高了心肌细胞诱导效率。 D PMID
  • 研究发现，树龄是银杏叶中总双花色素含量的主要负调节因素。 D PMID
  • GbMYB15 被鉴定为银杏属Ginkgo biloba中总黄酮合成的负调节剂，通过与Gb34759相互作用减少黄酮含量。 D PMID
  • 银杏叶提取物作为心力衰竭的辅助疗法显示出潜力，但证据有限且需要在更大规模的研究中进行验证。 A PMID
  • 前期研究提示银杏可能通过多种机制发挥神经保护作用，但临床数据不足以支持常规使用。 A PMID
  • 最近的技术创新改善了银杏提取物中生物活性化合物的提取和递送。 A PMID
  • 该研究识别出了银杏（Ginkgo biloba）中与纤维素、半纤维素和木质素生物合成相关的关键基因，有助于我们对木材特性和次生细胞壁发育的理解。 D PMID
  • 外源性聚胺可以促进银杏（Ginkgo biloba）初愈组织向胚胎状愈伤组织或球形胚阶段的转化，影响激素水平和基因表达。 D PMID
  • 研究确定了银杏乙种皮中银杏酸生物合成的关键基因和细胞机制。 D PMID
  • 银杏叶的剂量范围广泛变化，较高剂量（≥240 毫克/日）与症状性人群的认知功能改善相关。 D PMID

药物相互作用

  • 抗凝血药物 / 抗血小板药物 — 可能增加出血风险 B NCCIH

Frequently asked questions

What is ginkgo?

ginkgo (Ginkgo biloba) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is ginkgo traditionally used for?

Traditional sources record ginkgo for: 认知和循环支持（传统）. This reflects traditional use, not a proven medical treatment.

Which traditions use ginkgo?

ginkgo appears in these traditions in our sources: Western phytotherapy.

What does the scientific evidence say about ginkgo?

11 sourced findings are recorded for ginkgo; the strongest carries evidence grade A. For example: 研究显示，银杏叶提取物中的银杏内酯B和槲皮素可能作为天然的补体调节剂通过稳定与C3和C5蛋白的相互作用。

How strong is the evidence for ginkgo?

The strongest finding for ginkgo carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is ginkgo safe? What are the side effects?

No major safety issues are recorded for ginkgo in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does ginkgo interact with medications?

Recorded drug interactions for ginkgo involve: 抗凝血药物 / 抗血小板药物. Tell your doctor or pharmacist about any herb you take.

What are the common names of ginkgo?

ginkgo is also known as: гинкго.

Is ginkgo a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 NCCIH: Ginkgo public domain (attribute NCCIH)
  2. T2 Advanced extraction to targeted delivery: A holistic review of technological innovations and therapeutic mechanisms of Ginkgo biloba extract. literature abstract metadata
  3. T2 Ginkgo biloba as a Promising Candidate for Traumatic Brain Injury: Insights From Preclinical and Clinical Studies. literature abstract metadata
  4. T2 Ginkgolide A Enhances Cardiomyocyte Differentiation from Pluripotent Stem Cells by Targeting Cytochrome c to Attenuate Intrinsic Apoptosis. literature abstract metadata
  5. T2 Complement-Modulating Mechanisms of Ginkgo biloba Extract in Dry AMD: Insights From Molecular Docking and Dynamics Simulations. literature abstract metadata
  6. T2 Identification and functional analysis of GbMYB15 as a negative regulator in flavonoid biosynthesis of Ginkgo biloba. literature abstract metadata
  7. T2 Evaluating dosing guidelines for Ginkgo biloba: An evidence-based approach to standardisation. literature abstract metadata
  8. T2 Single-nucleus sequencing and spatial metabolomics analysis reveal the regulatory mechanism of ginkgolic acid biosynthesis in the episperm of Ginkgo biloba. literature abstract metadata
  9. T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
  10. T2 Polyamine-Related Gene Families Identification and Regulatory Effects on Early Somatic Embryogenesis via Modulating Gene Expressions and Hormone Levels in Ginkgo biloba. literature abstract metadata
  11. T2 Patterns of Biflavonoid Accumulation in Ginkgo (Ginkgo biloba L.) Leaves from 90 Trees and Their Variation with Age, Gender, and Location. literature abstract metadata
  12. T2 Revealing the genetic regulation of wood traits and secondary cell wall development in Ginkgo biloba: an integrated analysis from the perspectives of GWAS, TWAS, and WGCNA. literature abstract metadata