FolkKB

Madras carpet

Grangea maderaspatana

Grangea maderaspatana is a plant traditionally not associated with any known medicinal use. Scientific studies have shown that (-) Frullanolide from this plant exhibits aromatase inhibitor activity similar to reference medications used in breast cancer treatment, suggesting potential therapeutic applications. Additionally, 7-α-Hydroxyfrullanolide has demonstrated anti-cancer effects in triple-negative breast cancer (TNBC) cells through mechanisms involving G2/M-phase arrest and apoptosis. While the plant is found among local medicinal species near the Guangxi Fangcheng Golden Camellias national nature reserve, further research is warranted to fully understand its potential uses. No significant safety issues or known drug interactions have been recorded for Grangea maderaspatana.

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 研究记录了396种药用植物，包括Grangea maderaspatana，在广西方城金花茶国家自然保护区附近的当地居民使用。 D PMID
  • 来自Grangea maderaspatana的7-α-羟基弗鲁兰醇苷在TNBC细胞中通过G2/M期阻滞和凋亡表现出抗肿瘤作用。 D PMID
  • 化合物 (-)-Frullanolide 在抑制芳香化酶方面的效果与用于乳腺癌治疗的参考药物相似。 D PMID
  • 研究发现，零耕作技术的采用与某些杂草种类的相对密度较低有关，但整个群落水平上差异并不显著。 D PMID

Frequently asked questions

What is Madras carpet?

Madras carpet (Grangea maderaspatana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Madras carpet?

4 sourced findings are recorded for Madras carpet; the strongest carries evidence grade D. For example: 研究记录了396种药用植物，包括Grangea maderaspatana，在广西方城金花茶国家自然保护区附近的当地居民使用。

How strong is the evidence for Madras carpet?

The strongest finding for Madras carpet carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Madras carpet safe? What are the side effects?

No major safety issues are recorded for Madras carpet in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Madras carpet interact with medications?

No drug interactions are recorded for Madras carpet in our sources. This does not rule them out — check with a pharmacist.

Is Madras carpet a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Anticancer Effects and Molecular Action of 7-α-Hydroxyfrullanolide in G2/M-Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cells. literature abstract metadata
  2. T2 Weed germinable seedbanks of rice-wheat systems in the Eastern Indo-Gangetic Plains: Do tillage and edaphic factors explain community variation? literature abstract metadata
  3. T2 The medicinal plant used in the Guangxi Fangcheng Golden Camellias national nature reserve, a coastal region in southern China. literature abstract metadata
  4. T2 Targeting Breast Adenocarcinoma with Grangea maderaspatana Natural Compounds: A Molecular Docking and Pharmacokinetic Study. literature abstract metadata