FolkKB

Broadleaf Gumweed

Grindelia squarrosa

Grindelia squarrosa，这种植物传统上在美国原住民医学中用于各种状况，但没有特定的传统用途记录。研究表明，它对Strongyloides papillosus幼虫具有中等的杀线虫活性，并与其他植物一起使用。科学证据表明，从Inula helenium和Grindelia squarrosa提取物可以抑制中性粒细胞迁移和炎症细胞因子释放，类似于budesonide，这可能暗示潜在的抗炎作用。Grindelia squarrosa的精油含有α-蒎烯、柠檬烯和萜品醇等单萜类化合物，(-)-β-蒎烯对肺炎链球菌具有强烈的抗菌活性。此外，其精油中的(-)-薄荷醇调节人类中性粒细胞的活动。迄今为止，尚未记录Grindelia squarrosa的重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Grindelia squarrosa 在研究中对Strongyloides papillosus 蚧虫的活性表现出中等水平，并与其他植物种类一起。 D PMID
  • 研究发现，从Inula helenium和Grindelia squarrosa提取的成分可以抑制中性粒细胞迁移和炎症细胞因子释放，类似于budesonide的效果。 D PMID
  • 来自美国南部爱达荷州的Grindelia squarrosa精油含有α-蒎烯、柠檬烯和萜品醇等单萜类化合物，(-)-β-蒎烯对肺炎链球菌具有很强的抗菌活性。 D PMID
  • 研究发现，来自Grindelia squarrosa精油的(-)-冰片可调节人类中性粒细胞活性。 D PMID
  • Grędelia squarrosa 提取物调节了呼吸道上皮和巨噬细胞的促炎功能，但没有抗菌活性。 D PMID

Frequently asked questions

What is Broadleaf Gumweed?

Broadleaf Gumweed (Grindelia squarrosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Broadleaf Gumweed?

5 sourced findings are recorded for Broadleaf Gumweed; the strongest carries evidence grade D. For example: Grindelia squarrosa 在研究中对Strongyloides papillosus 蚧虫的活性表现出中等水平，并与其他植物种类一起。

How strong is the evidence for Broadleaf Gumweed?

The strongest finding for Broadleaf Gumweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Broadleaf Gumweed safe? What are the side effects?

No major safety issues are recorded for Broadleaf Gumweed in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Broadleaf Gumweed interact with medications?

No drug interactions are recorded for Broadleaf Gumweed in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Broadleaf Gumweed?

Broadleaf Gumweed is also known as: Гринделия растопыренная, Grindélia squarreux.

Is Broadleaf Gumweed a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium. literature abstract metadata
  2. T2 Grindelia squarrosa Extract and Grindelic Acid Modulate Pro-inflammatory Functions of Respiratory Epithelium and Human Macrophages. literature abstract metadata
  3. T2 Nematicidal activity of aqueous tinctures of plants against larvae of the nematode Strongyloides papillosus. literature abstract metadata
  4. T2 Neutrophil Immunomodulatory Activity of (-)-Borneol, a Major Component of Essential Oils Extracted from Grindelia squarrosa. literature abstract metadata
  5. T2 Essential Oil Composition of Grindelia squarrosa from Southern Idaho. literature abstract metadata