FolkKB

Broadleaf Gumweed

Grindelia squarrosa

Grindelia squarrosa，一种原产于北美的传统草药，在历史或文化医疗实践中没有广泛记录。科学研究表明，从Grindelia squarrosa和其他植物提取物可以表现出中等的线虫杀灭活性对抗Strongyloides papillosus幼虫，尽管这一发现尚处于初步阶段。此外，研究表明Grindelia squarrosa精油含有如(-)-β-蒎烯这样的单萜类化合物，显示出对肺炎链球菌的强大抗菌活性。从Inula helenium和Grindelia squarrosa提取物已被观察到抑制中性粒细胞迁移并释放炎症细胞因子，类似于布地奈德，表明潜在的抗炎作用。虽然没有记录到主要的安全问题或药物相互作用，但需要进一步研究以全面了解植物的有效性和安全性。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Grindelia squarrosa 在研究中对Strongyloides papillosus 蚧虫的活性表现出中等水平，并与其他植物种类一起。 D PMID
  • 研究发现，从Inula helenium和Grindelia squarrosa提取的成分可以抑制中性粒细胞迁移和炎症细胞因子释放，类似于budesonide的效果。 D PMID
  • 来自美国南部爱达荷州的Grindelia squarrosa精油含有α-蒎烯、柠檬烯和萜品醇等单萜类化合物，(-)-β-蒎烯对肺炎链球菌具有很强的抗菌活性。 D PMID
  • 研究发现，来自Grindelia squarrosa精油的(-)-冰片可调节人类中性粒细胞活性。 D PMID
  • Grędelia squarrosa 提取物调节了呼吸道上皮和巨噬细胞的促炎功能，但没有抗菌活性。 D PMID

Frequently asked questions

What is Broadleaf Gumweed?

Broadleaf Gumweed (Grindelia squarrosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Broadleaf Gumweed?

5 sourced findings are recorded for Broadleaf Gumweed; the strongest carries evidence grade D. For example: Grindelia squarrosa 在研究中对Strongyloides papillosus 蚧虫的活性表现出中等水平，并与其他植物种类一起。

How strong is the evidence for Broadleaf Gumweed?

The strongest finding for Broadleaf Gumweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Broadleaf Gumweed safe? What are the side effects?

No major safety issues are recorded for Broadleaf Gumweed in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Broadleaf Gumweed interact with medications?

No drug interactions are recorded for Broadleaf Gumweed in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Broadleaf Gumweed?

Broadleaf Gumweed is also known as: Гринделия растопыренная, Grindélia squarreux.

Is Broadleaf Gumweed a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium. literature abstract metadata
  2. T2 Grindelia squarrosa Extract and Grindelic Acid Modulate Pro-inflammatory Functions of Respiratory Epithelium and Human Macrophages. literature abstract metadata
  3. T2 Nematicidal activity of aqueous tinctures of plants against larvae of the nematode Strongyloides papillosus. literature abstract metadata
  4. T2 Neutrophil Immunomodulatory Activity of (-)-Borneol, a Major Component of Essential Oils Extracted from Grindelia squarrosa. literature abstract metadata
  5. T2 Essential Oil Composition of Grindelia squarrosa from Southern Idaho. literature abstract metadata