FolkKB

Five-leaf gynostemma

Gynostemma pentaphyllum

五味子（也称为夹竹桃）是一种传统中药，源自东亚医学。尽管其具体用途在传统实践中没有充分记录，但研究表明它具有多种健康益处的潜力。科学证据表明，从这种植物中提取的GpNAC68可以提高转基因阿拉伯芥对干旱的耐受性，并且nar，该植物中的另一种化合物，可能减少高脂饮食诱导条件下小鼠泡沫细胞形成并改善其血脂水平，这可能表明五味子在动脉粥样硬化治疗方面的应用潜力。此外，观察到五味子显著降低了患者空腹血糖、HbA1c和餐后2小时血糖水平，暗示了对管理血糖水平的潜在益处。GpGAB和GpGIB介导的时间延迟负反馈回路也表明，在茉莉酸诱导下，五味子中的人参皂苷生物合成存在复杂的调控机制。迄今为止，尚未发现与使用五味子相关的重大安全问题或药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 这项研究在景天三叶草中鉴定了86个GpNAC基因，并发现GpNAC68可以增强转基因拟南芥的抗旱性。 D PMID
  • nar，来自五味子属植物 Gynostemma pentaphyllum，体外减少了泡沫细胞形成，并改善了由高脂饮食诱导的ApoE-/-小鼠的血脂谱，表明其治疗动脉粥样硬化的潜在价值。 D PMID
  • 冬凌草显著降低了空腹血糖、HbA1c和餐后两小时血糖水平。 A PMID
  • JA诱导后，涉及GpGAB和GpGIB的时间延迟负反馈回路调节景天三叶草中甘草皂苷的生物合成。 D PMID
  • Gynostemma pentaphyllum 提取物在保护免受 H2O2 引起的过氧化压力并减少小鼠毛发变白方面显示出潜力。 D PMID

Frequently asked questions

What is Five-leaf gynostemma?

Five-leaf gynostemma (Gynostemma pentaphyllum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Five-leaf gynostemma?

5 sourced findings are recorded for Five-leaf gynostemma; the strongest carries evidence grade A. For example: 这项研究在景天三叶草中鉴定了86个GpNAC基因，并发现GpNAC68可以增强转基因拟南芥的抗旱性。

How strong is the evidence for Five-leaf gynostemma?

The strongest finding for Five-leaf gynostemma carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Five-leaf gynostemma safe? What are the side effects?

No major safety issues are recorded for Five-leaf gynostemma in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Five-leaf gynostemma interact with medications?

No drug interactions are recorded for Five-leaf gynostemma in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Five-leaf gynostemma?

Five-leaf gynostemma is also known as: Гиностемма пятилистная.

Is Five-leaf gynostemma a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Efficacy and mechanisms of Gynostemma pentaphyllum as a medicine food homology herb in glycemic control: a meta-analysis with review. literature abstract metadata
  2. T2 Narcissoside attenuates atherosclerosis by suppressing CD36-mediated foam cell formation via upregulation of NR4A1. literature abstract metadata
  3. T2 Comprehensive genome-wide mining and characterization of the NAC transcription factor family in Gynostemma pentaphyllum identifies GpNAC68 as a positive regulator of drought tolerance in transgenic Arabidopsis. literature abstract metadata
  4. T2 The Role of Gynostemma pentaphyllum Extract in Combating H2O2-Induced Oxidative Stress and Preventing Hair Graying. literature abstract metadata
  5. T2 Time-delayed activator-repressor regulation of ginsenoside biosynthesis in Gynostemma pentaphyllum. literature abstract metadata