Helicia nilagirica
Helicia nilagirica
Helicia nilagirica 是一种传统上不用于医疗目的的植物。其完整的叶绿体基因组已被描述，包含132个基因，并表明与 Macadamia integrifolia 有密切关系。科学研究显示，该植物中的活性成分 helicid 可以通过调节 SERTs 和 cAMP/PKA/CREB 信号通路改善慢性应激下大鼠的抑郁行为、学习能力和认知功能。此外，helicid 还表现出作为镇痛药和催眠药的潜力，可以减少神经病理性疼痛模型小鼠的机械性痛觉过敏并增加非快速眼动睡眠。从 Helicia nilagirica 的种子中分离出了五种化合物，其中三种是该属内首次报道的。尚未记录与这种植物相关的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Helicia nilagirica 的活性成分 helicid 在慢性应激条件下改善了大鼠的抑郁行为、学习和认知功能，通过调节 SERTs 和 cAMP/PKA/CREB 信号通路。
- Helicia nilagirica 的活性成分 helicid 显示出作为镇痛药和催眠药的潜力，减少了机械性痛觉过敏并增加了神经病理性疼痛模型小鼠的非快速眼动睡眠。
- Helicia nilagirica 的完整叶绿体基因组被表征，包含 132 个基因，并且与 Macadamia integrifolia 有密切关系。
- Five compounds were isolated from Helicia nilagirica seeds, with three previously unreported in the genus.
Frequently asked questions
What is Helicia nilagirica?
Helicia nilagirica (Helicia nilagirica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Helicia nilagirica?
4 sourced findings are recorded for Helicia nilagirica; the strongest carries evidence grade D. For example: Helicia nilagirica 的活性成分 helicid 在慢性应激条件下改善了大鼠的抑郁行为、学习和认知功能，通过调节 SERTs 和 cAMP/PKA/CREB 信号通路。
How strong is the evidence for Helicia nilagirica?
The strongest finding for Helicia nilagirica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Helicia nilagirica safe? What are the side effects?
No major safety issues are recorded for Helicia nilagirica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Helicia nilagirica interact with medications?
No drug interactions are recorded for Helicia nilagirica in our sources. This does not rule them out — check with a pharmacist.
Is Helicia nilagirica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 [Study on chemical constituents in seeds of Helicia nilagirica (II)]. literature abstract metadata
- T2 Helicid alleviates pain and sleep disturbances in a neuropathic pain-like model in mice. literature abstract metadata
- T2 Helicid Ameliorates Learning and Cognitive Ability and Activities cAMP/PKA/CREB Signaling in Chronic Unpredictable Mild Stress Rats. literature abstract metadata
- T2 Complete chloroplast genome of Helicia nilagirica Bedd. and its phylogenetic analysis. literature abstract metadata