Dungwort
Helleborus foetidus
Helleborus foetidus 是一种传统上没有特定药用用途的植物。科学证据表明，寄生在花蜜中的酵母显著改变了其花朵中蔗糖的浓度，减少了个体植株之间的差异。该植物含有 bufadienolides 和 19-norbufadienolides，这些物质对 MCF-7 乳腺癌细胞显示出不同的细胞毒性活性，这表明潜在的抗癌作用。此外，研究在 Helleborus foetidus 中鉴定了 28 种甾体苷，其中 20 种是新的，一些表现出对某些癌细胞的细胞毒性活性。目前尚未记录该植物的安全性问题和已报告的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 寄生在花蜜中的酵母显著改变了 Helleborus foetidus 花朵中蔗糖的浓度，减少了单株植物之间的可检测差异。
- 从Helleborus foetidus中分离出十二种bufadienolide和六种19-norbufadienolide，显示对MCF-7乳腺癌细胞具有差异性细胞毒活性。
- 研究回顾了来自各种植物的407种多羟基螺旋甾烷皂苷，其中欧防风即是其中一个来源。
- 研究在毛茛属臭菘中鉴定了28个甾体苷，其中20个是新的，并发现某些化合物对某些癌细胞具有细胞毒性活性。
Frequently asked questions
What is Dungwort?
Dungwort (Helleborus foetidus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dungwort?
4 sourced findings are recorded for Dungwort; the strongest carries evidence grade D. For example: 寄生在花蜜中的酵母显著改变了 Helleborus foetidus 花朵中蔗糖的浓度，减少了单株植物之间的可检测差异。
How strong is the evidence for Dungwort?
The strongest finding for Dungwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dungwort safe? What are the side effects?
No major safety issues are recorded for Dungwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dungwort interact with medications?
No drug interactions are recorded for Dungwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dungwort?
Dungwort is also known as: Hellébore fétide.
Is Dungwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Novel Steroidal Glycosides from the Whole Plants of Helleborus foetidus. literature abstract metadata
- T2 Naturally Occurring Polyhydroxylated Spirostanol Saponins, A Review of the Classification, Sources, Biosynthesis, Biological Activities, and Toxicity. literature abstract metadata
- T2 Bufadienolides from Helleborus foetidus and their cytotoxic properties on MCF-7 breast cancer cells. literature abstract metadata
- T2 Flowers as fungal extended phenotypes: nectar yeasts obfuscate among-plant differences in nectar sugar concentration. literature abstract metadata