Dungwort
Helleborus foetidus
Helleborus foetidus，通常称为臭天竺葵，是一种在欧洲和亚洲传统上发现的植物。尽管没有记录特定的传统用途，但该植物因其化学组成和潜在的生物学活性而进行了研究。科学数据表明，寄生在花蜜中的酵母显著改变了臭天竺葵花朵中蔗糖的浓度，这可能会影响其自然变异。此外，从这种植物中分离出了十二种 Bufadienolides 和六种 19-norbufadienolides，显示出对 MCF-7 乳腺癌细胞的不同细胞毒性活性。该植物还含有甾体苷，包括二十个新发现的，其中一些具有对某些癌细胞的细胞毒性活性。然而，总体科学证据有限，需要更多研究来全面了解其潜在的医学应用。值得注意的是，在现有研究中没有记录臭天竺葵的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 寄生在花蜜中的酵母显著改变了 Helleborus foetidus 花朵中蔗糖的浓度，减少了单株植物之间的可检测差异。
- Twelve bufadienolides and six 19-norbufadienolides were isolated from Helleborus foetidus, showing differential cytotoxic activity against MCF-7 breast cancer cells.
- 研究回顾了来自各种植物的407种多羟基螺旋甾烷皂苷，其中欧防风即是其中一个来源。
- 研究在毛茛属臭菘中鉴定了28个甾体苷，其中20个是新的，并发现某些化合物对某些癌细胞具有细胞毒性活性。
Frequently asked questions
What is Dungwort?
Dungwort (Helleborus foetidus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dungwort?
4 sourced findings are recorded for Dungwort; the strongest carries evidence grade D. For example: 寄生在花蜜中的酵母显著改变了 Helleborus foetidus 花朵中蔗糖的浓度，减少了单株植物之间的可检测差异。
How strong is the evidence for Dungwort?
The strongest finding for Dungwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dungwort safe? What are the side effects?
No major safety issues are recorded for Dungwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dungwort interact with medications?
No drug interactions are recorded for Dungwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dungwort?
Dungwort is also known as: Hellébore fétide.
Is Dungwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Novel Steroidal Glycosides from the Whole Plants of Helleborus foetidus. literature abstract metadata
- T2 Naturally Occurring Polyhydroxylated Spirostanol Saponins, A Review of the Classification, Sources, Biosynthesis, Biological Activities, and Toxicity. literature abstract metadata
- T2 Bufadienolides from Helleborus foetidus and their cytotoxic properties on MCF-7 breast cancer cells. literature abstract metadata
- T2 Flowers as fungal extended phenotypes: nectar yeasts obfuscate among-plant differences in nectar sugar concentration. literature abstract metadata