Bitter Oleander
Holarrhena pubescens
Holarrhena pubescens 是一种传统上在印度阿育吠陀实践中使用的植物。尽管这种植物的具体传统用途没有很好地记录，但已注意到从 Holarrhena pubescens 中提取的多种甾体生物碱在体外对 Trypanosoma brucei rhodesiense 和 Plasmodium falciparum 表现出抗原虫活性，这表明其可能具有抗疟疾作用。此外，一项研究发现，从其叶片提取物中生物合成的铜纳米簇可以进行选择性胆红素检测。科学证据还表明，Holarrhena pubescens 对万古霉素耐药肠球菌（VRE）表现出抗菌活性，并与万古霉素和cefoxitin显示出协同作用，可能减少生物膜形成。迄今为止，尚未记录该植物的重大安全问题或药物相互作用，但进一步的研究对于完全了解其潜在应用和效果是必要的。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 霍拉伦纳（pubescens）树叶提取物生物合成的铜纳米簇在生物体液中显示出对胆红素的选择性检测。
- 该审查确定了40种用于马尔巴南（Mayurbhanj）、奥里萨邦（Odisha）疟疾治疗的植物物种。
- 研究从Holarrhena pubescens中鉴定出几种甾体生物碱，具有体外抗Trypanosoma brucei rhodesiense和Plasmodium falciparum活性。
- PBN 展示了对 VRE 的抗菌活性，与万古霉素和cephoxitin 显示协同作用，并减少了生物膜的形成。
Frequently asked questions
What is Bitter Oleander?
Bitter Oleander (Holarrhena pubescens) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bitter Oleander?
4 sourced findings are recorded for Bitter Oleander; the strongest carries evidence grade A. For example: 霍拉伦纳（pubescens）树叶提取物生物合成的铜纳米簇在生物体液中显示出对胆红素的选择性检测。
How strong is the evidence for Bitter Oleander?
The strongest finding for Bitter Oleander carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Bitter Oleander safe? What are the side effects?
No major safety issues are recorded for Bitter Oleander in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bitter Oleander interact with medications?
No drug interactions are recorded for Bitter Oleander in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bitter Oleander?
Bitter Oleander is also known as: ecorce de conessie.
Is Bitter Oleander a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Biosynthesis of copper nanoclusters for fluorescence detection of bilirubin in biofluids. literature abstract metadata
- T2 A review on the ethnomedicinal plants used for the traditional treatment of malaria in the Mayurbhanj district of Odisha, India. literature abstract metadata
- T2 Pubescine as a Novel Antibacterial Agent Against Vancomycin-Resistant Enterococcus: Growth Inhibition, Antibiotic Synergy, and Anti-Biofilm Activity. literature abstract metadata
- T2 Identification of Steroidal Alkaloids with In Vitro Antiprotozoal Activity from Holarrhena pubescens Wall. ex G. Don. literature abstract metadata