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Houpoea officinalis

Houpoea officinalis

胡泊拉克（Houpoea officinalis）是一种传统上在东方亚洲医学中使用的植物，特别是在中国草药实践中。它与多种用途相关，如治疗消化系统疾病和改善整体健康状况，但关于胡泊拉克的具体传统用途记录不多。科学证据表明，从胡泊拉克中提取的honokiol可能通过抑制肝星状细胞激活在肝脏疾病的管理中有潜在益处。此外，研究表明胡泊拉克属植物的叶绿体基因表现出典型的四联结构，具有不同的基因内容和重复序列。更广泛地说，在健康应用方面，来自magnolol（M27）的一种衍生物在秀丽隐杆线虫中显示出增强的抗衰老效果，通过ROS减少和DAF-16途径激活机制实现。临床试验还表明，包括胡泊拉克在内的中国草药（CHM），与非治疗或常规对照组相比，显著降低了COVID-19、流感和严重肺炎加重的发生率。从安全性来看，目前没有记录到胡泊拉克的主要问题，并且尚未报告有关药物相互作用的问题。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • honokiol（来自胡椒树Houpoea officinalis）抑制肝星状细胞的激活并促进其失活通过诱导溶酶体膜通透性和损害脂质自噬。 D PMID
  • 三种Houpoea物种的叶绿体基因组被测序，并发现它们是典型的四分体，具有不同的基因含量和重复序列。 D PMID
  • CHM显著减少了COVID-19、流感和严重肺炎加重的发生率，与未治疗或常规对照组相比。 A PMID
  • 研究发现，来自 magnolol 的衍生物（M27）在 C. elegans 中表现出增强的抗衰老效果，通过减少 ROS 和激活 DAF-16 路径来延长健康寿命和寿命。 D PMID

Frequently asked questions

What is Houpoea officinalis?

Houpoea officinalis (Houpoea officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Houpoea officinalis?

4 sourced findings are recorded for Houpoea officinalis; the strongest carries evidence grade A. For example: honokiol（来自胡椒树Houpoea officinalis）抑制肝星状细胞的激活并促进其失活通过诱导溶酶体膜通透性和损害脂质自噬。

How strong is the evidence for Houpoea officinalis?

The strongest finding for Houpoea officinalis carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Houpoea officinalis safe? What are the side effects?

No major safety issues are recorded for Houpoea officinalis in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Houpoea officinalis interact with medications?

No drug interactions are recorded for Houpoea officinalis in our sources. This does not rule them out — check with a pharmacist.

Is Houpoea officinalis a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Synthesis, anti-aging and mechanism of magnolol derivatives. literature abstract metadata
  2. T2 Comparitive Analysis of the Chloroplast Genomes of Three Houpoea Plants. literature abstract metadata
  3. T2 An updated meta-analysis of Chinese herbal medicine for the prevention of COVID-19 based on Western-Eastern medicine. literature abstract metadata
  4. T2 Honokiol ameliorates hepatic fibrosis by inducing lysosomal membrane permeabilization and impairing lipophagy in hepatic stellate cells. literature abstract metadata