Bangahpul (East Asian soup-mint)
Isodon japonicus
日本铁线莲是一种传统上在一些东亚草药实践中使用的植物，但没有具体的传统用途记录。研究表明，其活性成分光果苷A可能通过抑制SRC/PI3K/AKT信号通路和诱导凋亡来抑制非小细胞肺癌（NSCLC）的增殖，从而显示出潜在的治疗效果。此外，网络药理学研究还表明，光果苷A也可能通过影响α-亚麻酸代谢、PTGS2、PLA2G15、EGFR、MMP9和PI3K/AKT/mTOR信号通路等关键途径来减轻牙周炎并减少溃疡性结肠炎小鼠的炎症。尽管没有记录到重大安全问题或药物相互作用，但进一步的研究是必要的以全面了解其疗效及其潜在应用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究发现，glaucocalyxin A 可通过抑制 PI3K/AKT/mTOR 信号通路来减少溃疡性结肠炎小鼠的炎症。
- RB 抑制NSCLC 进展并诱导凋亡，通过抑制SRC/PI3K/AKT信号通路。
- 研究确定α-亚麻酸代谢是甘草酸A可能在非小细胞肺癌中发挥治疗作用的关键途径，靶向PTGS2、PLA2G15和EGFR。
- 网络药理学和生物实验表明，来自日本益母草的Glaucocalyxin A可能抑制MMP9并抑制促炎细胞因子分泌，从而潜在地减轻牙周炎。
Frequently asked questions
What is Bangahpul (East Asian soup-mint)?
Bangahpul (East Asian soup-mint) (Isodon japonicus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bangahpul (East Asian soup-mint)?
4 sourced findings are recorded for Bangahpul (East Asian soup-mint); the strongest carries evidence grade D. For example: 这项研究发现，glaucocalyxin A 可通过抑制 PI3K/AKT/mTOR 信号通路来减少溃疡性结肠炎小鼠的炎症。
How strong is the evidence for Bangahpul (East Asian soup-mint)?
The strongest finding for Bangahpul (East Asian soup-mint) carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bangahpul (East Asian soup-mint) safe? What are the side effects?
No major safety issues are recorded for Bangahpul (East Asian soup-mint) in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bangahpul (East Asian soup-mint) interact with medications?
No drug interactions are recorded for Bangahpul (East Asian soup-mint) in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bangahpul (East Asian soup-mint)?
Bangahpul (East Asian soup-mint) is also known as: Прутьевик японский.
Is Bangahpul (East Asian soup-mint) a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Glaucocalyxin A alleviates ulcerative colitis by inhibiting PI3K/AKT/mTOR signaling. literature abstract metadata
- T2 Investigating the therapeutic mechanism of glaucocalyxin A in non-small cell lung cancer through integrated network pharmacology, metabolomics, molecular docking, and molecular dynamics simulations. literature abstract metadata
- T2 Network pharmacology analysis and biological validation of molecular targets regulated by glaucocalyxin a in periodontitis. literature abstract metadata
- T2 Rabdosin B suppresses proliferation of nonsmall cell lung cancer by regulating the SRC/PI3K/AKT signaling pathway. literature abstract metadata