Kleinhovia
Kleinhovia
克莱尼霍维亚是一种传统上在各种草药实践中使用的植物，尽管其具体用途尚未充分记录。科学研究表明，从克莱尼霍维亚 hospita 中提取的物质具有显著的抗疟疾活性，对抗 P. falciparum（导致疟疾的寄生虫）表现出明显的抑制作用。此外，从克莱尼霍维亚 hospita 分离出的一些化合物，如 kleinhospitine A、β-阿米林和卡斯蒂尔酚，显示出作为 cathepsin L 抑制剂的潜力，并且与 schinol 相比具有较低的结合能。这些提取物还表现出对金黄色葡萄球菌（Staphylococcus aureus）的体外抗菌活性，而不会影响成纤维细胞的毒性或增殖。尽管从克莱尼霍维亚 hospita 中分离和表征了几种化合物，包括新的环artenoids，但未发现显著的健康影响。安全记录表明，这种植物没有记录到主要问题，并且根据当前的研究结果，它尚未报告与任何药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 七种提取物，包括一种来自克莱因霍维亚·霍斯塔的提取物，对P. 恶性疟原虫显示出显著的抗疟活性。
- 克莱因霍维亚·霍斯塔（Kleinhovia hospita）化合物kleinhospitine A、β-阿米林和卡斯提尔酚显示出作为猫头鹰蛋白酶L抑制剂的潜力，其结合能量低于施尼洛。
- 研究从Kleinhovia hospita中鉴定出几种新的环-artanian三萜，具有不同的结构和生物活性。
- Kleinhovia hospita 提取物在体外对金黄色葡萄球菌表现出抗菌活性，且不对人类真皮成纤维细胞产生毒性。
Frequently asked questions
What is Kleinhovia?
Kleinhovia (Kleinhovia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kleinhovia?
4 sourced findings are recorded for Kleinhovia; the strongest carries evidence grade D. For example: 七种提取物，包括一种来自克莱因霍维亚·霍斯塔的提取物，对P. 恶性疟原虫显示出显著的抗疟活性。
How strong is the evidence for Kleinhovia?
The strongest finding for Kleinhovia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kleinhovia safe? What are the side effects?
No major safety issues are recorded for Kleinhovia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kleinhovia interact with medications?
No drug interactions are recorded for Kleinhovia in our sources. This does not rule them out — check with a pharmacist.
Is Kleinhovia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita. literature abstract metadata
- T2 In vitro antibacterial activity of extracts from Samoan medicinal plants and their effect on proliferation and migration of human fibroblasts. literature abstract metadata
- T2 Molecular modeling for potential cathepsin L inhibitor identification as new anti-photoaging agents from tropical medicinal plants. literature abstract metadata
- T2 Evaluation of the antiplasmodial and anti-Toxoplasma activities of several Indonesian medicinal plant extracts. literature abstract metadata