FolkKB

edelweiss

Leontopodium nivale

Leontopodium nivale，通常称为雪绒花，是一种传统上生长在阿尔卑斯山的植物，在任何传统医学实践中没有特定记录的应用。科学研究已经确定了该植物中的一些化合物，包括leoligin，这些化合物可能具有作为PDE4抑制剂的潜力，尽管其在此角色中的有效性证据有限且需要进一步研究。此外，研究表明Leontopodium nivale subsp. alpinum菌株中有551个次级代谢物生物合成基因簇，这表明可能存在抗菌活性和新生物活性化合物的潜在发现。然而，在这项研究中没有观察到对测试过的炎症途径有显著影响。目前的安全性问题很小，尚未记录重大问题；同样，也没有报告药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 六种化合物，包括莱奥林吉宁，被鉴定为潜在的PDE4抑制剂，其中一种类似物LT-104A显示出与已知抑制剂相当的活性。 D PMID
  • 研究在来自Leontopodium nivale subsp. alpinum的Streptomyces菌株中鉴定了551个次级代谢生物合成基因簇，从而发现了具有潜在抗菌活性的新分子。 D PMID
  • 研究在从莱蒙托夫雪兔子ssp. 阿尔皮努姆分离出的Streptomyces spp.中鉴定了214个次级代谢物生物合成基因簇，这可能产生新的生物活性化合物。 D PMID
  • 在本研究中，Leontopodium nivale 在测试的炎症途径上未显示出显著效果。 D PMID

Frequently asked questions

What is edelweiss?

edelweiss (Leontopodium nivale) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about edelweiss?

4 sourced findings are recorded for edelweiss; the strongest carries evidence grade D. For example: 六种化合物，包括莱奥林吉宁，被鉴定为潜在的PDE4抑制剂，其中一种类似物LT-104A显示出与已知抑制剂相当的活性。

How strong is the evidence for edelweiss?

The strongest finding for edelweiss carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is edelweiss safe? What are the side effects?

No major safety issues are recorded for edelweiss in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does edelweiss interact with medications?

No drug interactions are recorded for edelweiss in our sources. This does not rule them out — check with a pharmacist.

What are the common names of edelweiss?

edelweiss is also known as: Эдельвейс альпийский, edelweiss des Alpes.

Is edelweiss a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Genomes and secondary metabolomes of Streptomyces spp. isolated from Leontopodium nivale ssp. alpinum. literature abstract metadata
  2. T2 Selected Plant Extracts Regulating the Inflammatory Immune Response and Oxidative Stress: Focus on Quercus robur. literature abstract metadata
  3. T2 Secondary Metabolite Biosynthesis Potential of Streptomyces Spp. from the Rhizosphere of Leontopodium nivale Subsp. alpinum. literature abstract metadata
  4. T2 Identification of a novel PDE4 inhibitor inspired by leoligin-derived lignans. literature abstract metadata