FolkKB

edelweiss

Leontopodium nivale

Leontopodium nivale，又称雪绒花，是一种传统的阿尔卑斯山植物，起源于欧洲阿尔卑斯山脉。尽管其在传统医学中的使用尚未广泛记录，但研究已识别出潜在的药理作用。研究表明，六种化合物，包括leoligin，可能作为PDE4抑制剂发挥作用，并表现出与已知抑制剂相当的活性。此外，在Leontopodium nivale subsp. alpinum的streptomyces菌株中发现了551个次级代谢物生物合成基因簇，这表明有潜在的新抗菌分子。该植物还显示出在其他测试提取物中ROS产生方面的显著效果。迄今为止尚未记录到重大安全问题或药物相互作用，但进一步研究对于完全了解其医学应用和潜在益处是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 六种化合物，包括莱奥林吉宁，被鉴定为潜在的PDE4抑制剂，其中一种类似物LT-104A显示出与已知抑制剂相当的活性。 D PMID
  • 研究在来自Leontopodium nivale subsp. alpinum的Streptomyces菌株中鉴定了551个次级代谢生物合成基因簇，从而发现了具有潜在抗菌活性的新分子。 D PMID
  • 研究在从莱蒙托夫雪兔子ssp. 阿尔皮努姆分离出的Streptomyces spp.中鉴定了214个次级代谢物生物合成基因簇，这可能产生新的生物活性化合物。 D PMID
  • 在本研究中，Leontopodium nivale 在测试的炎症途径上未显示出显著效果。 D PMID

Frequently asked questions

What is edelweiss?

edelweiss (Leontopodium nivale) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about edelweiss?

4 sourced findings are recorded for edelweiss; the strongest carries evidence grade D. For example: 六种化合物，包括莱奥林吉宁，被鉴定为潜在的PDE4抑制剂，其中一种类似物LT-104A显示出与已知抑制剂相当的活性。

How strong is the evidence for edelweiss?

The strongest finding for edelweiss carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is edelweiss safe? What are the side effects?

No major safety issues are recorded for edelweiss in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does edelweiss interact with medications?

No drug interactions are recorded for edelweiss in our sources. This does not rule them out — check with a pharmacist.

What are the common names of edelweiss?

edelweiss is also known as: Эдельвейс альпийский, edelweiss des Alpes.

Is edelweiss a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Genomes and secondary metabolomes of Streptomyces spp. isolated from Leontopodium nivale ssp. alpinum. literature abstract metadata
  2. T2 Selected Plant Extracts Regulating the Inflammatory Immune Response and Oxidative Stress: Focus on Quercus robur. literature abstract metadata
  3. T2 Secondary Metabolite Biosynthesis Potential of Streptomyces Spp. from the Rhizosphere of Leontopodium nivale Subsp. alpinum. literature abstract metadata
  4. T2 Identification of a novel PDE4 inhibitor inspired by leoligin-derived lignans. literature abstract metadata