FolkKB

Mediterranean mandrake

Mandragora officinarum

曼德拉草（Mandragora officinarum），又称曼特拉克，是一种传统植物，与多种文化和民间传说相关。尽管其在特定传统中用于医疗目的的使用情况没有广泛记录，但该植物曾在波斯医学文献中被提及，并建议逐渐替代鸦片以管理成瘾问题。科学研究主要集中在毒理学方面以及生物碱如氢甲基卡因和颠茄碱的存在上，这些是具有抗胆碱能作用的莨菪碱类生物碱。这些化合物已被临床使用，但其传统用途仍待进一步探索。一项研究对几种茄科植物中的这些生物碱进行了定量分析，在曼德拉草样本中发现了不同浓度或缺乏活性成分的情况。值得注意的是，迄今为止没有记录到该植物存在显著的安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 研究量化了四种茄科植物中的东莨菪碱和颠茄碱含量，在分析样品中发现了不同浓度或不存在。 D PMID
  • 该研究回顾了十二种植物标本（包括曼陀罗属 officinarum）中精神活性物质的毒理学方面、传统用途和分析方法。 D PMID
  • 曼德拉草 officinarum 含有颠茄类生物碱，具有抗胆碱能作用，在各种医疗应用中使用，尽管其确切的临床影响仍存在争议。 D PMID
  • 研究发现波斯医学建议逐渐减少鸦片的使用，并用曼德拉草等其他植物替代，以管理成瘾问题。 D PMID

Frequently asked questions

What is Mediterranean mandrake?

Mediterranean mandrake (Mandragora officinarum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Mediterranean mandrake?

4 sourced findings are recorded for Mediterranean mandrake; the strongest carries evidence grade D. For example: 研究量化了四种茄科植物中的东莨菪碱和颠茄碱含量，在分析样品中发现了不同浓度或不存在。

How strong is the evidence for Mediterranean mandrake?

The strongest finding for Mediterranean mandrake carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Mediterranean mandrake safe? What are the side effects?

No major safety issues are recorded for Mediterranean mandrake in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Mediterranean mandrake interact with medications?

No drug interactions are recorded for Mediterranean mandrake in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Mediterranean mandrake?

Mediterranean mandrake is also known as: Мандрагора лекарственная, mandragore.

Is Mediterranean mandrake a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples. literature abstract metadata
  2. T2 Treatment of opium addiction in persian medicine: A review study. literature abstract metadata
  3. T2 Beauty of the beast: anticholinergic tropane alkaloids in therapeutics. literature abstract metadata
  4. T2 Simultaneous quantification of hyoscyamine and scopolamine using HPLC-DAD in four Solanaceae: Hyoscyamus niger, Datura stramonium, Atropa belladonna and Mandragora officinarum. literature abstract metadata