FolkKB

Malabar Nutmeg

Myristica malabarica

Myristica malabarica，这种植物传统上没有记录的医学用途，在科学研究中显示出前景。研究表明其果皮中含有几种具有适度抗增殖活性的化合物，特别是对A2780人类卵巢癌细胞和三阴性乳腺癌细胞。值得注意的是，malabaricone C 降低了T淋巴细胞的增殖并减少了细胞因子的分泌，可能有助于管理小鼠急性移植物抗宿主病。尽管ML-20在乳腺癌细胞中显示出增强的抗增殖作用和放射敏感性，但证据仍处于初步阶段，需要更多研究来确认这些发现。目前没有记录到与Myristica malabarica相关的重大安全问题或药物相互作用，但在推荐任何临床应用之前还需要进一步调查。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 一种新型的马巴罗辛酮衍生物（ML-20）在乳腺癌细胞中显示出增强的抗增殖作用和放射敏化特性。 D PMID
  • 马拉巴里康C抑制T细胞增殖和细胞因子分泌，减少小鼠急性移植物抗宿主病的严重程度。 D PMID
  • 研究发现，来自Myristica malabarica果实果皮的八种已知化合物对A2780人卵巢癌细胞具有中等程度的抗增殖活性。 D PMID
  • 马拉巴里康A在具有凋亡能力和涉及内外途径的三阴性乳腺癌细胞中显示出增强毒性。 D PMID

Frequently asked questions

What is Malabar Nutmeg?

Malabar Nutmeg (Myristica malabarica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Malabar Nutmeg?

4 sourced findings are recorded for Malabar Nutmeg; the strongest carries evidence grade D. For example: 一种新型的马巴罗辛酮衍生物（ML-20）在乳腺癌细胞中显示出增强的抗增殖作用和放射敏化特性。

How strong is the evidence for Malabar Nutmeg?

The strongest finding for Malabar Nutmeg carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Malabar Nutmeg safe? What are the side effects?

No major safety issues are recorded for Malabar Nutmeg in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Malabar Nutmeg interact with medications?

No drug interactions are recorded for Malabar Nutmeg in our sources. This does not rule them out — check with a pharmacist.

Is Malabar Nutmeg a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Anti-Proliferative Acyl Phenols and Arylnonanoids from the Fruit Rind of Myristica malabarica Lam. literature abstract metadata
  2. T2 Malabaricone C, a constituent of spice Myristica malabarica, exhibits anti-inflammatory effects via modulation of cellular redox. literature abstract metadata
  3. T2 Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of Myristica malabarica Lam. literature abstract metadata
  4. T2 Synthesis, Structure-Activity Relationship, and Biological Evaluation of a Novel Malabaricone Derivative: A Potent Anticancer Agent and Radiosensitizer That Targets Autophagy Flux. literature abstract metadata