FolkKB

picrorhiza

Neopicrorhiza scrophulariiflora

印度茜草（Neopicrorhiza scrophulariiflora），又称印度菝葜或奇拉雅塔，是一种传统药用植物，在阿育吠陀和其他印度草药实践中被使用。尽管其具体用途尚未广泛记录，但研究强调了它在肝脏保护方面的潜在益处。该植物中的一种化合物Picrocylide A显示出了对乙酰氨基酚诱导的细胞损伤具有强大的肝保护活性。此外，研究还确定了43个候选基因可能参与picroside-I和picroside-II的生物合成，这有助于理解其化学机制。值得注意的是，传统中医与西医治疗相结合在严重急性胰腺炎相关的急性肺损伤/ARDS患者中改善了临床疗效和炎症标志物；然而，进一步的研究是必要的以确认这些发现。目前关于印度茜草的安全性问题较小，尚未记录任何重大问题。此外，目前没有报告药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 吡咯里西定A，来自朱卡托尔（Neopicrorhiza scrophulariiflora）的一种化合物，在对乙酰氨基酚诱导的细胞损伤中表现出强大的肝保护活性。 D PMID
  • 研究确定了参与茜草属根中三萜生物合成的关键基因，从而增强了对其化学生产机制的理解。 D PMID
  • 研究确定了43个候选基因，可能参与了从牛防己中合成picroside-I和picroside-II的过程。 D PMID
  • 中医疗法与西医药结合在严重急性胰腺炎相关急性肺损伤/ARDS患者中显著改善了临床疗效和炎症标志物，尽管存在一些限制。 A PMID
  • 尼佩科罗里扎（Neopicrorhiza scrophulariiflora）是51种记录在案的植物物种中被夏尔巴人最常使用的药用物质之一。 D PMID

Frequently asked questions

What is picrorhiza?

picrorhiza (Neopicrorhiza scrophulariiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about picrorhiza?

5 sourced findings are recorded for picrorhiza; the strongest carries evidence grade A. For example: 吡咯里西定A，来自朱卡托尔（Neopicrorhiza scrophulariiflora）的一种化合物，在对乙酰氨基酚诱导的细胞损伤中表现出强大的肝保护活性。

How strong is the evidence for picrorhiza?

The strongest finding for picrorhiza carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is picrorhiza safe? What are the side effects?

No major safety issues are recorded for picrorhiza in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does picrorhiza interact with medications?

No drug interactions are recorded for picrorhiza in our sources. This does not rule them out — check with a pharmacist.

Is picrorhiza a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Traditional medicinal knowledge of Sherpa people: Assessment in Xizang, China. literature abstract metadata
  2. T2 Integrative analysis of metabolite and transcriptome reveals the biosynthetic pathway and candidate genes for iridoid glycoside biosynthesis in Neopicrorhiza scrophulariiflora (Pennell) D.Y.Hong. literature abstract metadata
  3. T2 Multi-Omics and Functional Insights into Triterpenoid Biosynthesis Pathways in Neopicrorhiza scrophulariiflora (Pennell) D.Y.Hong. literature abstract metadata
  4. T2 Picrocylide A: A Cyclobutane-Containing Apocarotenoid-Derived Meroterpenoid from Neopicrorhiza scrophulariiflora with Hepatoprotective Effect. literature abstract metadata
  5. T2 Assessment of the efficacy of Chinese herbal medicine combined with western medicine for treating severe acute pancreatitis-related acute lung injury/acute respiratory distress syndrome: a systematic review and meta-analysis based on random literature abstract metadata