FolkKB

picrorhiza

Neopicrorhiza scrophulariiflora

Neopicrorhiza scrophulariiflora，又称非洲朱梅或卡姆赫，是一种传统药物，在阿育吠陀和其他印度医学系统中被使用。传统上，它用于各种状况，包括炎症、发热和皮肤疾病，但具体用途可能因不同的传统而异。 科学数据表明，Neopicrorhiza scrophulariiflora 含有如 picrocylide A 等化合物，这些化合物对乙酰氨基酚诱导的肝损伤具有强大的保护作用。此外，研究还确定了参与三萜生物合成的关键基因，这增强了对其化学生产机制和潜在治疗应用的理解。一项元分析表明，将中医与西医结合可显著提高严重急性胰腺炎相关急性肺损伤/急性呼吸窘迫综合征（SAP-ALI/ARDS）患者的临床疗效，尽管证据仍然有限。 尚未记录 Neopicrorhiza scrophulariiflora 的重大安全问题，并未报告药物相互作用。然而，进一步的研究对于全面了解其在各种临床环境中的潜在益处和风险是必要的。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 吡咯里西定A，来自朱卡托尔（Neopicrorhiza scrophulariiflora）的一种化合物，在对乙酰氨基酚诱导的细胞损伤中表现出强大的肝保护活性。 D PMID
  • 研究确定了参与茜草属根中三萜生物合成的关键基因，从而增强了对其化学生产机制的理解。 D PMID
  • 研究确定了43个候选基因，可能参与了从牛防己中合成picroside-I和picroside-II的过程。 D PMID
  • 中医疗法与西医药结合在严重急性胰腺炎相关急性肺损伤/ARDS患者中显著改善了临床疗效和炎症标志物，尽管存在一些限制。 A PMID
  • 尼佩科罗里扎（Neopicrorhiza scrophulariiflora）是51种记录在案的植物物种中被夏尔巴人最常使用的药用物质之一。 D PMID

Frequently asked questions

What is picrorhiza?

picrorhiza (Neopicrorhiza scrophulariiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about picrorhiza?

5 sourced findings are recorded for picrorhiza; the strongest carries evidence grade A. For example: 吡咯里西定A，来自朱卡托尔（Neopicrorhiza scrophulariiflora）的一种化合物，在对乙酰氨基酚诱导的细胞损伤中表现出强大的肝保护活性。

How strong is the evidence for picrorhiza?

The strongest finding for picrorhiza carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is picrorhiza safe? What are the side effects?

No major safety issues are recorded for picrorhiza in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does picrorhiza interact with medications?

No drug interactions are recorded for picrorhiza in our sources. This does not rule them out — check with a pharmacist.

Is picrorhiza a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Traditional medicinal knowledge of Sherpa people: Assessment in Xizang, China. literature abstract metadata
  2. T2 Integrative analysis of metabolite and transcriptome reveals the biosynthetic pathway and candidate genes for iridoid glycoside biosynthesis in Neopicrorhiza scrophulariiflora (Pennell) D.Y.Hong. literature abstract metadata
  3. T2 Multi-Omics and Functional Insights into Triterpenoid Biosynthesis Pathways in Neopicrorhiza scrophulariiflora (Pennell) D.Y.Hong. literature abstract metadata
  4. T2 Picrocylide A: A Cyclobutane-Containing Apocarotenoid-Derived Meroterpenoid from Neopicrorhiza scrophulariiflora with Hepatoprotective Effect. literature abstract metadata
  5. T2 Assessment of the efficacy of Chinese herbal medicine combined with western medicine for treating severe acute pancreatitis-related acute lung injury/acute respiratory distress syndrome: a systematic review and meta-analysis based on random literature abstract metadata