FolkKB

Pilocarpus

Pilocarpus

Pilocarpus 是一种传统上用于多种民间医学实践的植物属，尽管各个物种的具体传统用途尚未得到充分记录。科学证据表明其潜在益处，包括使用 episiopiloturine 可降低心脏缺血再灌注实验中大鼠的房室传导阻滞和致死率。此外，来自 Pilocarpus 的化合物通过自噬调节和抗炎作用减轻了小鼠肝毒性。Pilocarpus microphyllus 的基因组装配为研究其 pilocarpine 生物合成奠定基础。体外实验表明，Pilocarpus microphyllus 精油具有抗利什曼病、细胞毒性和弱抗真菌活性。目前尚未记录到重大安全问题或已知药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Epiisopiloturine（15 mg/kg）预处理减少了心脏缺血和再灌注实验中大鼠的房室传导阻滞和死亡率。 D PMID
  • Pilocarpus microphyllus 挥发油显示出抗利什曼原虫、细胞毒性和弱抗真菌活性。 D PMID
  • 该研究呈现了Pilocarpus microphyllus的染色体水平基因组装，为其吡洛卡品生物合成的研究奠定了基础。 D PMID
  • 从Pilocarpus attenuatus中提取的环氧西波林和环氧西波托林通过自噬调节和抗炎作用减轻了小鼠对扑热息痛诱导的肝毒xing。 D PMID

Frequently asked questions

What is Pilocarpus?

Pilocarpus (Pilocarpus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pilocarpus?

4 sourced findings are recorded for Pilocarpus; the strongest carries evidence grade D. For example: Epiisopiloturine（15 mg/kg）预处理减少了心脏缺血和再灌注实验中大鼠的房室传导阻滞和死亡率。

How strong is the evidence for Pilocarpus?

The strongest finding for Pilocarpus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pilocarpus safe? What are the side effects?

No major safety issues are recorded for Pilocarpus in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pilocarpus interact with medications?

No drug interactions are recorded for Pilocarpus in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Pilocarpus?

Pilocarpus is also known as: Пилокарпус.

Is Pilocarpus a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Evaluation of Potential Molecular Targets of the Alkaloid Epiisopiloturine, Involved in Cardioprotective Effects, Using Computational Molecular Docking in an Animal Model of Cardiac Ischemia and Reperfusion. literature abstract metadata
  2. T2 Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study. literature abstract metadata
  3. T2 Imidazole Alkaloids Epiisopilosine and Epiisopiloturine Attenuate Acetaminophen-Induced Liver Toxicity in Mice via Autophagy Modulation and Anti-Inflammatory Effects. literature abstract metadata
  4. T2 De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction. literature abstract metadata