FolkKB

Pilocarpus

Pilocarpus

Pilocarpus 是一种传统上与南美洲，尤其是巴西的多种土著文化相关联的植物。尽管其具体的传统用途尚未详细记录，但已对其潜在的医疗益处进行了研究。科学证据表明，从 Pilocarpus 中提取的化合物，如 epiisopiloturine 和 epiisopilosine，在缺血和再灌注期间可能对心脏具有保护作用，有可能减少心肌损伤标志物并降低房室传导阻滞的发生率。此外，这些化合物在通过自噬调节和抗炎机制减轻由对乙酰氨基酚引起的肝毒性方面显示出希望。Pilocarpus microphyllus 的精油表现出抗利什曼原虫、细胞毒性和弱抗真菌活性。尚未报告该植物的重大安全问题或已知药物相互作用，但进一步研究对于完全了解其潜在的治疗应用是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Epiisopiloturine（15 mg/kg）预处理减少了心脏缺血和再灌注实验中大鼠的房室传导阻滞和死亡率。 D PMID
  • Pilocarpus microphyllus 挥发油显示出抗利什曼原虫、细胞毒性和弱抗真菌活性。 D PMID
  • 该研究呈现了Pilocarpus microphyllus的染色体水平基因组装，为其吡洛卡品生物合成的研究奠定了基础。 D PMID
  • 从Pilocarpus attenuatus中提取的环氧西波林和环氧西波托林通过自噬调节和抗炎作用减轻了小鼠对扑热息痛诱导的肝毒xing。 D PMID

Frequently asked questions

What is Pilocarpus?

Pilocarpus (Pilocarpus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pilocarpus?

4 sourced findings are recorded for Pilocarpus; the strongest carries evidence grade D. For example: Epiisopiloturine（15 mg/kg）预处理减少了心脏缺血和再灌注实验中大鼠的房室传导阻滞和死亡率。

How strong is the evidence for Pilocarpus?

The strongest finding for Pilocarpus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pilocarpus safe? What are the side effects?

No major safety issues are recorded for Pilocarpus in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pilocarpus interact with medications?

No drug interactions are recorded for Pilocarpus in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Pilocarpus?

Pilocarpus is also known as: Пилокарпус.

Is Pilocarpus a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Evaluation of Potential Molecular Targets of the Alkaloid Epiisopiloturine, Involved in Cardioprotective Effects, Using Computational Molecular Docking in an Animal Model of Cardiac Ischemia and Reperfusion. literature abstract metadata
  2. T2 Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study. literature abstract metadata
  3. T2 Imidazole Alkaloids Epiisopilosine and Epiisopiloturine Attenuate Acetaminophen-Induced Liver Toxicity in Mice via Autophagy Modulation and Anti-Inflammatory Effects. literature abstract metadata
  4. T2 De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction. literature abstract metadata