Blister Bush
Plumbago zeylanica
Plumbago zeylanica，通常被称为印度铅草或马拉巴尔铅木，是一种传统药用植物，在印度及亚洲其他地区的各种民间实践中使用。虽然其具体用途尚未得到广泛记录，但它传统上用于治疗创伤、皮肤疾病和消化问题。科学证据表明，来自该植物的成分——plumbagin，对耐碳培南类抗生素的Acinetobacter baumannii具有显著的抗菌活性，然而尚未进行人类临床试验以确定其在治疗剂量下的疗效。此外，该化合物已显示出剂量依赖性的毒蛇蛋白酶和胶原酶抑制作用，并且在体内具有保护效果而不产生明显毒性。 一项研究记录了125种药用植物，指出女性往往比男性更了解植物的用途。尚未发现该植物存在主要安全问题或已报告的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 该研究成功地在酵母中重建了没食子酸的生物合成途径，确认了六个基因的功能作用，并建立了可持续生产没食子酸的平台。
- 来自Plumbago zeylanica的没食子酸表现出对碳青霉烯耐药Acinetobacter baumannii显著的抗菌和生物膜破坏活性，但未测试任何临床剂量。
- PZE 展现了剂量依赖性对毒液蛋白酶和胶原酶活性的抑制作用，保持了纤维蛋白原的完整性，并在体内表现出保护作用而无显著毒性。
- 该研究记录了125种药用植物，女性对植物用途的了解程度高于男性。
Frequently asked questions
What is Blister Bush?
Blister Bush (Plumbago zeylanica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Blister Bush?
4 sourced findings are recorded for Blister Bush; the strongest carries evidence grade D. For example: 该研究成功地在酵母中重建了没食子酸的生物合成途径，确认了六个基因的功能作用，并建立了可持续生产没食子酸的平台。
How strong is the evidence for Blister Bush?
The strongest finding for Blister Bush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Blister Bush safe? What are the side effects?
No major safety issues are recorded for Blister Bush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Blister Bush interact with medications?
No drug interactions are recorded for Blister Bush in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Blister Bush?
Blister Bush is also known as: Plombago de Ceylan.
Is Blister Bush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Ethnobotanical heritage and conservation priorities of medicinal flora in a remote Himalayan border region of Azad Kashmir, Pakistan. literature abstract metadata
- T2 De novo synthesis of plant polyketide plumbagin in yeast: a platform for sustainable production of naphthoquinones. literature abstract metadata
- T2 Plumbagin Disrupts Biofilm Integrity and Resistance Gene Expression in Carbapenem-Resistant Acinetobacter baumannii. literature abstract metadata
- T2 Ethnopharmacological evaluation of Plumbago zeylanica L. against Russell's viper envenomation: a combined computational and experimental study. literature abstract metadata