FolkKB

American Mandrake

Podophyllum peltatum

北美千叶木（Podophyllum peltatum）是一种多年生草本植物，原产于北美，被广泛应用于各种传统医学体系。历史上，它曾被用作泻药、催吐剂和缓泻剂，以治疗肝脏疾病、黄疸、胆道问题和肠道功能紊乱，以及梅毒、发烧、疣和驱虫。科学研究主要集中在其生物合成途径以及其衍生物（如鬼臼毒素）在抗癌药物递送系统中的应用潜力，或作为依托泊苷合成的中间体。目前，关于其在人体中的临床疗效的证据有限。现有数据中未记录任何重大的安全问题或显著的药物相互作用。

速览
传统用于
胆汁的 · 肝脏问题
传统体系
传统
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

传统用途

科学怎么说

  • 研究发现，在生长季节不同时间固定的碳被以不同方式利用，且在Podophyllum peltatum中各个季节之间的再分配有限，这影响了其人口统计学。 D PMID
  • 研究评估了负载有podophyllotoxin或 juniper提取物的胶束作为潜在抗癌药物载体的用途。 D PMID
  • 这项研究建立了一种基于酵母的高效途径，用于生产(-)-4'-去甲基-乙基纤维素毒素，这是依托泊苷合成中的中间体。 D PMID
  • 研究成功克隆并分析了参与白花蛇舌草中podophyllotoxin生物合成的关键基因ShOMT3。 D PMID

Frequently asked questions

What is American Mandrake?

American Mandrake (Podophyllum peltatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is American Mandrake traditionally used for?

Traditional sources record American Mandrake for: 胆汁的, 肝脏问题, 泻药, 梅毒, 泻药, 胆汁. This reflects traditional use, not a proven medical treatment.

Which traditions use American Mandrake?

American Mandrake appears in these traditions in our sources: traditional.

What does the scientific evidence say about American Mandrake?

4 sourced findings are recorded for American Mandrake; the strongest carries evidence grade D. For example: 研究发现，在生长季节不同时间固定的碳被以不同方式利用，且在Podophyllum peltatum中各个季节之间的再分配有限，这影响了其人口统计学。

How strong is the evidence for American Mandrake?

The strongest finding for American Mandrake carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is American Mandrake safe? What are the side effects?

No major safety issues are recorded for American Mandrake in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does American Mandrake interact with medications?

No drug interactions are recorded for American Mandrake in our sources. This does not rule them out — check with a pharmacist.

What are the common names of American Mandrake?

American Mandrake is also known as: Подофилл щитовидный, Podophylle pelté.

Is American Mandrake a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Polycarbonate-Based Copolymer Micelles as Biodegradable Carriers of Anticancer Podophyllotoxin or Juniper Extracts. literature abstract metadata
  3. T2 Interactions between developmental phenology, carbon movement, and storage constrain demography in the understory clonal herb Podophyllum peltatum L. literature abstract metadata
  4. T2 Cloning and bioinformatics analysis of key gene ShOMT3 of podophyllotoxin biosynthesis pathway in Sinopodophyllum hexandrum. literature abstract metadata
  5. T2 A yeast-based platform for etoposide production via yatein bioconversion. literature abstract metadata