FolkKB

American Mandrake

Podophyllum peltatum

Podophyllum peltatum，又称mayapple或mandrake，是一种原产于北美的传统药用植物。它在美国土著和民间医学中用于多种用途，尽管其具体用途尚未得到充分记录。科学研究探索了它的生物化学特性，并揭示了碳在生长季节中的使用量会有所不同，而podophyllotoxin（一种活性成分）显示出作为抗癌剂的潜力。研究还表明可以从yatein中可持续生产etoposide，后者源自Podophyllum属植物。值得注意的是，这种植物没有显著的安全问题或已记录的药物相互作用，尽管进一步的研究正在进行以全面了解其特性和应用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • The study found that carbon fixed at different times in the growing season is used differently and there is limited redistribution between seasons in Podophyllum peltatum, affecting its demography. D PMID
  • 研究评估了负载有podophyllotoxin或 juniper提取物的胶束作为潜在抗癌药物载体的用途。 D PMID
  • 这项研究建立了一种基于酵母的高效途径，用于生产(-)-4'-去甲基-乙基纤维素毒素，这是依托泊苷合成中的中间体。 D PMID
  • 研究成功克隆并分析了参与白花蛇舌草中podophyllotoxin生物合成的关键基因ShOMT3。 D PMID

Frequently asked questions

What is American Mandrake?

American Mandrake (Podophyllum peltatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about American Mandrake?

4 sourced findings are recorded for American Mandrake; the strongest carries evidence grade D. For example: The study found that carbon fixed at different times in the growing season is used differently and there is limited redistribution between seasons in Podophyllum peltatum, affecting its demography.

How strong is the evidence for American Mandrake?

The strongest finding for American Mandrake carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is American Mandrake safe? What are the side effects?

No major safety issues are recorded for American Mandrake in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does American Mandrake interact with medications?

No drug interactions are recorded for American Mandrake in our sources. This does not rule them out — check with a pharmacist.

What are the common names of American Mandrake?

American Mandrake is also known as: Подофилл щитовидный, Podophylle pelté.

Is American Mandrake a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Polycarbonate-Based Copolymer Micelles as Biodegradable Carriers of Anticancer Podophyllotoxin or Juniper Extracts. literature abstract metadata
  2. T2 Interactions between developmental phenology, carbon movement, and storage constrain demography in the understory clonal herb Podophyllum peltatum L. literature abstract metadata
  3. T2 Cloning and bioinformatics analysis of key gene ShOMT3 of podophyllotoxin biosynthesis pathway in Sinopodophyllum hexandrum. literature abstract metadata
  4. T2 A yeast-based platform for etoposide production via yatein bioconversion. literature abstract metadata