FolkKB

Pogostemon cablin

Pogostemon cablin

薄荷龙胆（Patchouli），又称 Patchouli，是一种传统上在各种文化实践中使用的植物，特别是在芳香疗法和香水制造中。科学研究表明其具有潜在的抗癌作用，研究表明 Patchouli 醇 (PA) 可通过氧化应激积累和雄激素受体信号传导失活机制抑制肝细胞癌的生长。此外，研究还显示，测序方法在 Pogostemon cablin 中揭示了比基于培养的方法更大的微生物多样性，尽管两种方法都识别出了潜在病原体。PA 还激活胆汁酸 X 受体 (PXR) 来抑制 Wnt/β-连环蛋白信号传导和上皮-间充质转化（EMT），这可能有助于抑制与幽门螺杆菌相关的胃癌。薄荷龙胆的精油对埃及伊蚊具有显著的驱避作用，可提供长达 180 分钟的保护。安全记录未发现重大问题，并且目前没有已知的药物相互作用与此植物相关。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • PA 激活 PXR 以抑制 Wnt/β-连环蛋白信号传导和上皮-间质转化，可能抑制与 H. pylori 相关的胃癌。 D PMID
  • 百里香薄荷油膏对埃及伊蚊表现出显著的驱避作用，完全保护时间为180分钟。 D PMID
  • PA inhibited HCC growth through oxidative stress accumulation and androgen receptor signaling inactivation, with potential synergistic effects when combined with sorafenib. D PMID
  • 测序检测到Pogostemon cablin中的微生物多样性远大于基于培养的方法，尽管两者都识别出了潜在的病原体。 D PMID

Frequently asked questions

What is Pogostemon cablin?

Pogostemon cablin (Pogostemon cablin) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pogostemon cablin?

4 sourced findings are recorded for Pogostemon cablin; the strongest carries evidence grade D. For example: PA 激活 PXR 以抑制 Wnt/β-连环蛋白信号传导和上皮-间质转化，可能抑制与 H. pylori 相关的胃癌。

How strong is the evidence for Pogostemon cablin?

The strongest finding for Pogostemon cablin carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pogostemon cablin safe? What are the side effects?

No major safety issues are recorded for Pogostemon cablin in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pogostemon cablin interact with medications?

No drug interactions are recorded for Pogostemon cablin in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Pogostemon cablin?

Pogostemon cablin is also known as: пачули, Patchouli.

Is Pogostemon cablin a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Microbial profiling of five traditional Chinese medicines: culture-based identification vs. 16S rRNA sequencing. literature abstract metadata
  2. T2 Inhibitory effects of patchouli alcohol on hepatocellular carcinoma growth through accumulation of oxidative stress and inactivation of androgen receptor signaling. literature abstract metadata
  3. T2 Development and In Silico/In Vivo Evaluation of a Pogostemon cablin Essential Oil Cream as a Repellent against Aedes aegypti. literature abstract metadata
  4. T2 Patchouli alcohol suppresses Helicobacter pylori-associated gastric cancer by activating PXR to inhibit the Wnt/β-catenin pathway and EMT. literature abstract metadata