FolkKB

Pogostemon cablin

Pogostemon cablin

薄荷龙胆（Patchouli）来源于中国传统医学，广泛用于亚洲多种文化中。传统上，它因其芳香特性而被使用，并用于治疗皮肤状况，但具体用途在不同传统之间差异很大。研究表明，薄荷醇（PA），存在于薄荷龙胆中的化合物，可能通过激活PXR途径抑制Wnt/β-连环蛋白信号通路和胃癌细胞中与幽门螺杆菌相关的上皮-间质转化（EMT）而具有潜在的抗癌作用。此外，薄荷精油对埃及伊蚊有显著驱避活性，可提供长达180分钟的保护。体外研究表明，PA可以通过氧化应激积累和抑制雄激素受体信号通路来抑制肝细胞癌（HCC）生长，并且与索拉非尼联合使用时可能具有协同作用。虽然测序方法检测到比培养基方法更高的微生物多样性，但两种方法都识别出了潜在病原体。尚未发现薄荷龙胆存在重大安全问题或记录在案的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • PA 激活 PXR 以抑制 Wnt/β-连环蛋白信号传导和上皮-间质转化，可能抑制与 H. pylori 相关的胃癌。 D PMID
  • 百里香薄荷油膏对埃及伊蚊表现出显著的驱避作用，完全保护时间为180分钟。 D PMID
  • PA通过氧化应激积累和雄激素受体信号传导失活抑制HCC生长，在与索拉非尼联合使用时具有潜在的协同作用。 D PMID
  • 测序检测到Pogostemon cablin中的微生物多样性远大于基于培养的方法，尽管两者都识别出了潜在的病原体。 D PMID

Frequently asked questions

What is Pogostemon cablin?

Pogostemon cablin (Pogostemon cablin) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pogostemon cablin?

4 sourced findings are recorded for Pogostemon cablin; the strongest carries evidence grade D. For example: PA 激活 PXR 以抑制 Wnt/β-连环蛋白信号传导和上皮-间质转化，可能抑制与 H. pylori 相关的胃癌。

How strong is the evidence for Pogostemon cablin?

The strongest finding for Pogostemon cablin carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pogostemon cablin safe? What are the side effects?

No major safety issues are recorded for Pogostemon cablin in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pogostemon cablin interact with medications?

No drug interactions are recorded for Pogostemon cablin in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Pogostemon cablin?

Pogostemon cablin is also known as: пачули, Patchouli.

Is Pogostemon cablin a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Microbial profiling of five traditional Chinese medicines: culture-based identification vs. 16S rRNA sequencing. literature abstract metadata
  2. T2 Inhibitory effects of patchouli alcohol on hepatocellular carcinoma growth through accumulation of oxidative stress and inactivation of androgen receptor signaling. literature abstract metadata
  3. T2 Development and In Silico/In Vivo Evaluation of a Pogostemon cablin Essential Oil Cream as a Repellent against Aedes aegypti. literature abstract metadata
  4. T2 Patchouli alcohol suppresses Helicobacter pylori-associated gastric cancer by activating PXR to inhibit the Wnt/β-catenin pathway and EMT. literature abstract metadata