Pulmonaria obscura
Pulmonaria obscura
肺叶紫罗兰（Pulmonaria obscura），属于紫草科，传统上未在任何已知的医疗实践中使用。科学研究已经确定了17种物种中包括肺叶紫罗兰在内的茎部提取物中有6种活性化合物和根部提取物中的4种活性化合物，这突显了其潜在的药用价值。尽管肺叶紫罗兰的根和根状茎含有吡咯里西啶生物碱，但叶片和花序仅显示微量。提取物在血浆中部分缓解过氧亚硝酸盐诱导的氧化应激并抑制COX-2；然而，P. obscura与近缘种P. officinalis的效果有所不同。两种物种中的Yunnaneic acid B有效减轻了过氧亚硝酸盐诱导的氧化应激且未引起细胞毒性，表明潜在的抗氧化作用。迄今为止尚未记录肺叶紫罗兰的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究在17种紫草科植物的茎提取物中鉴定出了6种活性化合物，在根提取物中鉴定出了4种，其中包括紫罗兰幽闭症（Pulmonaria obscura）。
- Pulmonaria obscura 的根和根茎含有可检测的吡咯里西啶生物碱水平，而叶子和花序则含有微量。
- 来自Pulmonaria obscura和P. officinalis的提取物部分减轻了过氧亚硝酸盐诱导的血液浆液氧化应激，并显示出COX-2抑制活性，尽管物种之间存在差异。
- 来自肺叶草L.的Yunnaneic酸B有效地减少了由过氧亚硝基引起的体外氧化应激，且无细胞毒性。
Frequently asked questions
What is Pulmonaria obscura?
Pulmonaria obscura (Pulmonaria obscura) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pulmonaria obscura?
4 sourced findings are recorded for Pulmonaria obscura; the strongest carries evidence grade D. For example: 研究在17种紫草科植物的茎提取物中鉴定出了6种活性化合物，在根提取物中鉴定出了4种，其中包括紫罗兰幽闭症（Pulmonaria obscura）。
How strong is the evidence for Pulmonaria obscura?
The strongest finding for Pulmonaria obscura carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pulmonaria obscura safe? What are the side effects?
No major safety issues are recorded for Pulmonaria obscura in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pulmonaria obscura interact with medications?
No drug interactions are recorded for Pulmonaria obscura in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Pulmonaria obscura?
Pulmonaria obscura is also known as: Медуница неясная, Herbe-de-cœur.
Is Pulmonaria obscura a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Pyrrolizidine alkaloids in Pulmonaria obscura. literature abstract metadata
- T2 Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family. literature abstract metadata
- T2 Yunnaneic Acid B, a Component of Pulmonaria officinalis Extract, Prevents Peroxynitrite-Induced Oxidative Stress in Vitro. literature abstract metadata
- T2 Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. literature abstract metadata