Hawthorn-leaved Bramble

Rubus crataegifolius, also known as the thimbleberry, is a plant native to North America. While it has not been traditionally used in any specific medical practices or remedies, studies have shown promising results. In mice infected with CagA+ Helicobacter pylori, extracts from Rubus crataegifolius reduced bacterial levels and suppressed both acute and chronic inflammation. Additionally, four polysaccharides extracted from the roots demonstrated antioxidant activities and in vitro protective effects against H2O2-induced damage in HepG2 cells. The herbal complex also improved serum lipid profiles and reduced body weight and fat accumulation in mice fed a high-fat diet. In combination with Ulmus macrocarpa extracts, there was a synergistic effect against H. pylori, though individual minimum inhibitory concentrations were higher when used alone. No major safety issues or drug interactions have been recorded for Rubus crataegifolius, but further research is needed to confirm these findings in human studies.

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