FolkKB

Bloodroot

Sanguinaria canadensis

北美血根（Sanguinaria canadensis）是一种多年生草本植物，原产于北美，广泛应用于各种传统医学体系。历史上，它曾被用于治疗多种疾病，包括咳嗽、咽喉痛、烧伤、风湿和贫血，同时也被用作催吐剂或兴奋剂。初步的科学研究表明，其成分血根碱可能具有抗菌特性，可对抗金黄色葡萄球菌，并可能减轻小鼠体内顺铂引起的肾损伤。一些研究还表明，它在调节某些癌细胞的信号通路中发挥作用，但仍需要更多可靠的证据。目前，现有数据中未记录任何主要的安全性问题或显著的药物相互作用。

速览
传统用于
催吐的 · 祛痰药
传统体系
传统
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

传统用途

科学怎么说

  • 血根碱通过减轻炎症、氧化应激和细胞损伤，改善了小鼠顺铂诱导的急性肾损伤。 D PMID
  • 研究鉴定出来自11种传统药用植物（包括北美血根草）的多种植物成分，这些成分可以调节肺癌和结肠癌细胞中的关键信号通路。 D PMID
  • 血根碱表现出抗菌作用并干扰了金黄色葡萄球菌的生物膜形成，影响了膜完整性及IGPD活性。 D PMID
  • 研究发现，血根碱的肠道吸收显著受P-gp蛋白影响，并涉及多种转运机制。 D PMID

Frequently asked questions

What is Bloodroot?

Bloodroot (Sanguinaria canadensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Bloodroot traditionally used for?

Traditional sources record Bloodroot for: 催吐的, 祛痰药, 兴奋剂, 健胃药, 贫血, 烧伤. This reflects traditional use, not a proven medical treatment.

Which traditions use Bloodroot?

Bloodroot appears in these traditions in our sources: traditional.

What does the scientific evidence say about Bloodroot?

4 sourced findings are recorded for Bloodroot; the strongest carries evidence grade D. For example: 血根碱通过减轻炎症、氧化应激和细胞损伤，改善了小鼠顺铂诱导的急性肾损伤。

How strong is the evidence for Bloodroot?

The strongest finding for Bloodroot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Bloodroot safe? What are the side effects?

No major safety issues are recorded for Bloodroot in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Bloodroot interact with medications?

No drug interactions are recorded for Bloodroot in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Bloodroot?

Bloodroot is also known as: Sanguinaire du Canada.

Is Bloodroot a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Studies on pharmacokinetic properties and intestinal absorption mechanism of sanguinarine chloride: in vivo and in situ. literature abstract metadata
  3. T2 Targeting membrane integrity and imidazoleglycerol-phosphate dehydratase: Sanguinarine multifaceted approach against Staphylococcus aureus biofilms. literature abstract metadata
  4. T2 Interplay Between Traditional and Scientific Knowledge: Phytoconstituents and Their Roles in Lung and Colorectal Cancer Signaling Pathways. literature abstract metadata
  5. T2 Attenuation of cisplatin-induced acute kidney injury by sanguinarine: modulation of oxidative stress, inflammation, and cellular damage. literature abstract metadata