FolkKB

Orientvine

Sinomenium acutum

Sinomenium acutum，一种传统中药植物，在东亚草药实践中主要用于治疗。尽管其具体用途尚未广泛记录，但研究表明，其中含有的化合物sinomenine可能通过调节多种免疫成分来减轻实验性自身免疫性神经炎的临床严重程度和炎症浸润。此外，在迭代培养中观察到可培养内生菌，特别是Priestia aryabhattai，其组成显示出变化，并与Sinomenium acutum中的sinomenine含量相关。该植物表现出多种药理活性，尤其是对类风湿性关节炎；然而，关于相互作用和协同效应的研究有限。Sinomenine (SIN) 可通过三种不同的模式共价修饰蛋白质，在体内影响凝血和补体途径。迄今为止尚未报告主要的安全问题或药物相互作用。

速览
传统用于
镇痛药 · 关节炎
传统体系
日本（汉方） · 中医
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

传统用途

  • 镇痛药 日本（汉方） T3 DRDUKE
  • 关节炎 中医 T3 DRDUKE
  • 脚气病 中医 T3 DRDUKE
  • 驱气药 中医 T3 DRDUKE
  • 利尿剂 日本（汉方） T3 DRDUKE
  • 水肿 中医 T3 DRDUKE
  • 风湿病 中医 T3 DRDUKE

科学怎么说

  • 辛莫尼治疗减少了实验性自身免疫性神经炎的临床严重程度和炎症浸润，通过调节多种免疫成分。 D PMID
  • 研究发现，可培养内生菌，尤其是Priestia aryabhattai，在迭代培养过程中表现出组成上的变化，并与Sinomenium acutum中的sinomenine含量相关。 D PMID
  • SC具有多种药理活性，尤其是在类风湿性关节炎方面，但对其相互作用和协同效应的研究有限。 D PMID
  • 辛莫尼宁（SIN）可以通过三种不同的模式共价修饰蛋白质，影响体内凝血和补体途径。 D PMID

Frequently asked questions

What is Orientvine?

Orientvine (Sinomenium acutum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Orientvine traditionally used for?

Traditional sources record Orientvine for: 镇痛药, 关节炎, 脚气病, 驱气药, 利尿剂, 水肿. This reflects traditional use, not a proven medical treatment.

Which traditions use Orientvine?

Orientvine appears in these traditions in our sources: Japanese (Kampo), TCM.

What does the scientific evidence say about Orientvine?

4 sourced findings are recorded for Orientvine; the strongest carries evidence grade D. For example: 辛莫尼治疗减少了实验性自身免疫性神经炎的临床严重程度和炎症浸润，通过调节多种免疫成分。

How strong is the evidence for Orientvine?

The strongest finding for Orientvine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Orientvine safe? What are the side effects?

No major safety issues are recorded for Orientvine in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Orientvine interact with medications?

No drug interactions are recorded for Orientvine in our sources. This does not rule them out — check with a pharmacist.

Is Orientvine a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Iterative enrichment cultivation and multiomic analysis reveal potential endophytic bacteria affecting the sinomenine synthesis in Sinomenium acutum. literature abstract metadata
  3. T2 Sinomenine ameliorates experimental autoimmune neuritis by suppressing pro-inflammatory immune components and restoring immune balance. literature abstract metadata
  4. T2 Chemical proteomics reveals sinomenine's anti-inflammatory mechanism through serum protein covalent modification. literature abstract metadata
  5. T2 Botany, ethnopharmacology, phytochemistry, pharmacological activities, toxicity, quality control, clinical application and novel preparations of Sinomenii Caulis: An updated review. literature abstract metadata