nux-vomica

Strychnos nux-vomica

Strychnos nux-vomica 这种树原产于印度和斯里兰卡,在巨大的树木下生长,传统上与神圣的森林相关联。其在具体医疗实践中的使用记录不详。科学研究表明,特别是通过DES-UAE方法从种子中提取活性化合物显示出有希望的结果,并且突显了其抗氧化性质。临床前研究显示,Strychnos nux-vomica 中的布鲁金可能抑制各种癌症类型的肿瘤发展,尽管证据仍然有限,需要更多的研究来证实这些发现。不同加工方法的种子显示出不同程度的肝肾毒性降低,醋酸处理特别有效。虽然没有记录到主要的安全问题或药物相互作用,但由于其有毒性质,在处理生种子时应谨慎。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程,实现了高萃取率和抗氧化性能。 D PMID
  • 前期研究表明,从Strychnos nux-vomica中提取的布鲁金(Brucine)在多种癌症类型中对肿瘤发展显示出显著抑制作用。 D PMID
  • 不同加工的strychnos nux-vomica 种子产品显示出不同程度的肝肾毒性降低,其中醋制效果最为显著。 D PMID
  • 在神圣的林地中,strychnos nux-vomica 更多的是以幼苗的形式生长在大树下,而不是人类聚居地附近。 D PMID
  • 虚拟筛选识别出多种植物化学物质,包括来自Strychnos nux-vomica的4-羟基斯特里克宁,作为登革热病毒NS2B-NS3蛋白酶的潜在抑制剂。 D PMID

Frequently asked questions

What is nux-vomica?

nux-vomica (Strychnos nux-vomica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about nux-vomica?

5 sourced findings are recorded for nux-vomica; the strongest carries evidence grade D. For example: 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程,实现了高萃取率和抗氧化性能。

How strong is the evidence for nux-vomica?

The strongest finding for nux-vomica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is nux-vomica safe? What are the side effects?

No major safety issues are recorded for nux-vomica in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does nux-vomica interact with medications?

No drug interactions are recorded for nux-vomica in our sources. This does not rule them out — check with a pharmacist.

What are the common names of nux-vomica?

nux-vomica is also known as: Чилибуха.

Is nux-vomica a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Brucine as a Natural Modulator of Cancer Signaling: Cellular Mechanisms, Therapeutic Potential, and Translational Perspectives. literature abstract metadata
  2. T2 High-Throughput Virtual Screening of Phytochemicals From Indian Medicinal Plants for the Identification of Potential Inhibitors Against NS2B-NS3 Protease of Dengue Virus. literature abstract metadata
  3. T2 [Hepatotoxicity and renotoxicity of different processed products of Strychnos nux-vomica seeds based on serum metabolomics and their mechanisms of action]. literature abstract metadata
  4. T2 Optimization of phenolics recovery from strychnos nux-vomica L. seed applying deep eutectic solvent-ultrasound assisted extraction. literature abstract metadata
  5. T2 Giant trees enhance zoochorous plant dispersal in sacred groves and human settlements of the Western Ghats, India. literature abstract metadata