nux-vomica
Strychnos nux-vomica
乌头果（Strychnos nux-vomica）是一种植物，常见于神圣林地中巨树下的幼苗。在各种传统医学体系中，它被用作催吐剂、兴奋剂，并用于治疗包括癫痫、发烧、哮喘、绞痛和腹部不适等疾病。初步的科学证据表明，从种子中提取的乌头碱可能在临床前模型中对肿瘤生长产生抑制作用，并且某些处理方法（如醋处理）可能降低其对肝脏和肾脏的毒性。此外，提取的生物活性化合物还显示出很高的抗氧化特性。目前尚未记录到重大的安全问题或明显的药物相互作用。
- 传统用于
- 大麻 · 发烧
- 传统体系
- 中医 · 阿育吠陀 · 传统
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
传统用途
- 大麻
- 发烧
- 溃疡
- 兴奋剂
- 腹部不适
- 疟疾（疟热）
- 弱视
- 哮喘
- avicide
- 舞蹈症
- 中枢神经系统兴奋剂
- 绞痛
- 金雀花
- 催吐的
- 癫痫
科学怎么说
- 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程，实现了高萃取率和抗氧化性能。
- 前期研究表明，从Strychnos nux-vomica中提取的布鲁金（Brucine）在多种癌症类型中对肿瘤发展显示出显著抑制作用。
- 不同加工的strychnos nux-vomica 种子产品显示出不同程度的肝肾毒性降低，其中醋制效果最为显著。
- 在神圣的林地中，strychnos nux-vomica 更多的是以幼苗的形式生长在大树下，而不是人类聚居地附近。
- 虚拟筛选识别出多种植物化学物质，包括来自Strychnos nux-vomica的4-羟基斯特里克宁，作为登革热病毒NS2B-NS3蛋白酶的潜在抑制剂。
Frequently asked questions
What is nux-vomica?
nux-vomica (Strychnos nux-vomica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is nux-vomica traditionally used for?
Traditional sources record nux-vomica for: 大麻, 发烧, 溃疡, 兴奋剂, 腹部不适, 疟疾（疟热）. This reflects traditional use, not a proven medical treatment.
Which traditions use nux-vomica?
nux-vomica appears in these traditions in our sources: TCM, Ayurveda, traditional.
What does the scientific evidence say about nux-vomica?
5 sourced findings are recorded for nux-vomica; the strongest carries evidence grade D. For example: 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程，实现了高萃取率和抗氧化性能。
How strong is the evidence for nux-vomica?
The strongest finding for nux-vomica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is nux-vomica safe? What are the side effects?
No major safety issues are recorded for nux-vomica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does nux-vomica interact with medications?
No drug interactions are recorded for nux-vomica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of nux-vomica?
nux-vomica is also known as: Чилибуха.
Is nux-vomica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Brucine as a Natural Modulator of Cancer Signaling: Cellular Mechanisms, Therapeutic Potential, and Translational Perspectives. literature abstract metadata
- T2 High-Throughput Virtual Screening of Phytochemicals From Indian Medicinal Plants for the Identification of Potential Inhibitors Against NS2B-NS3 Protease of Dengue Virus. literature abstract metadata
- T2 [Hepatotoxicity and renotoxicity of different processed products of Strychnos nux-vomica seeds based on serum metabolomics and their mechanisms of action]. literature abstract metadata
- T2 Optimization of phenolics recovery from strychnos nux-vomica L. seed applying deep eutectic solvent-ultrasound assisted extraction. literature abstract metadata
- T2 Giant trees enhance zoochorous plant dispersal in sacred groves and human settlements of the Western Ghats, India. literature abstract metadata