nux-vomica
Strychnos nux-vomica
原产于印度和其他亚洲地区的Strychnos nux-vomica树在阿育吠陀医学中传统上被用于消化和驱虫。然而，并没有记录特定的传统用途。临床前研究表明，Strychnos nux-vomica中的布鲁辛表现出对各种癌症类型的肿瘤发展具有显著抑制作用，一些证据表明通过优化提取方法可以产生大量生物活性化合物。不同加工的种子显示出不同程度的肝肾毒性降低，特别是醋酸处理。该植物通常在神圣林地的大树下作为幼苗存在，而不是人类聚居区。没有记录到主要的安全问题或药物相互作用，但由于其毒性性质应谨慎使用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程，实现了高萃取率和抗氧化性能。
- 前期研究表明，从Strychnos nux-vomica中提取的布鲁金（Brucine）在多种癌症类型中对肿瘤发展显示出显著抑制作用。
- 不同加工的strychnos nux-vomica 种子产品显示出不同程度的肝肾毒性降低，其中醋制效果最为显著。
- 在神圣的林地中，strychnos nux-vomica 更多的是以幼苗的形式生长在大树下，而不是人类聚居地附近。
- The virtual screening identified several phytochemicals, including 4-hydroxystrychnine from Strychnos nux-vomica, as potential inhibitors against NS2B-NS3 protease of dengue virus.
Frequently asked questions
What is nux-vomica?
nux-vomica (Strychnos nux-vomica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about nux-vomica?
5 sourced findings are recorded for nux-vomica; the strongest carries evidence grade D. For example: 研究通过使用DES-UAE优化了从Strychnos nux-vomica种子中提取生物活性化合物的过程，实现了高萃取率和抗氧化性能。
How strong is the evidence for nux-vomica?
The strongest finding for nux-vomica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is nux-vomica safe? What are the side effects?
No major safety issues are recorded for nux-vomica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does nux-vomica interact with medications?
No drug interactions are recorded for nux-vomica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of nux-vomica?
nux-vomica is also known as: Чилибуха.
Is nux-vomica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Brucine as a Natural Modulator of Cancer Signaling: Cellular Mechanisms, Therapeutic Potential, and Translational Perspectives. literature abstract metadata
- T2 High-Throughput Virtual Screening of Phytochemicals From Indian Medicinal Plants for the Identification of Potential Inhibitors Against NS2B-NS3 Protease of Dengue Virus. literature abstract metadata
- T2 [Hepatotoxicity and renotoxicity of different processed products of Strychnos nux-vomica seeds based on serum metabolomics and their mechanisms of action]. literature abstract metadata
- T2 Optimization of phenolics recovery from strychnos nux-vomica L. seed applying deep eutectic solvent-ultrasound assisted extraction. literature abstract metadata
- T2 Giant trees enhance zoochorous plant dispersal in sacred groves and human settlements of the Western Ghats, India. literature abstract metadata