Taxus chinensis
Taxus chinensis
Taxus chinensis，又称中国云杉，是一种原产于东亚的传统草药植物。尽管它在亚洲多种传统草药疗法中被使用了几个世纪，但其具体传统用途尚未得到广泛记录。科学研究表明可能具有潜在的治疗应用；例如，研究表明从Taxus chinensis衍生的外泌体-顺铂纳米平台可以提高某些癌症（特别是三阴性乳腺癌TNBC）治疗的有效性并减少全身毒性。此外，Taxus片剂在抗肿瘤疗效方面与紫杉醇注射液相当，并且具有良好的耐受性，支持其作为口服抗肿瘤药物的潜力。来自Taxus chinensis var. mairei品种的化合物4和5在脂肪细胞中显示出显著降低甘油三酯活性，IC50值与非诺贝特相似，表明可能对脂质代谢有益。迄今为止尚未发现重大安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究介绍了一种源自红豆杉的外泌体顺铂纳米平台用于治疗三阴性乳腺癌，显示了增强的治疗效果并降低了系统毒性。
- Taxus片剂与PTX注射液在抗肿瘤疗效方面相当，并且耐受性良好，支持其作为口服抗肿瘤药物的发展。
- 洪武混合物（HWM）抑制三阴性乳腺癌细胞增殖并促进凋亡，通过调节ZNF143/SAV1信号通路。
- 来自Taxus chinensis var. mairei的化合物4和5在脂肪细胞中显示出显著降低甘油三酯活性，IC50值与苯氧布特相似。
Frequently asked questions
What is Taxus chinensis?
Taxus chinensis (Taxus chinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Taxus chinensis?
4 sourced findings are recorded for Taxus chinensis; the strongest carries evidence grade D. For example: 这项研究介绍了一种源自红豆杉的外泌体顺铂纳米平台用于治疗三阴性乳腺癌，显示了增强的治疗效果并降低了系统毒性。
How strong is the evidence for Taxus chinensis?
The strongest finding for Taxus chinensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Taxus chinensis safe? What are the side effects?
No major safety issues are recorded for Taxus chinensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Taxus chinensis interact with medications?
No drug interactions are recorded for Taxus chinensis in our sources. This does not rule them out — check with a pharmacist.
Is Taxus chinensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Hongwu mixture exerts inhibition on triple-negative breast cancer by regulating SAV1/Hippo signaling through ZNF143. literature abstract metadata
- T2 A semimechanistic PK/PD model-informed Taxus tablets' development: Accelerating early clinical translation of a taxane-based antitumor agent. literature abstract metadata
- T2 Intelligent plant exosomes synergize miRNAs and cisplatin for spatiotemporally precise multimodal treatment for TNBC with high safety. literature abstract metadata
- T2 2(3→20)-abeo-taxoids with adipogenesis inhibitory activity from the leaves and twigs of Taxus chinensis var. mairei. literature abstract metadata