Taxus chinensis
Taxus chinensis
Taxus chinensis 是一种传统的中国植物。尽管其在传统医学中的具体用途尚未详细记录，但现代研究显示了其潜在的抗肿瘤活性。研究表明，来自 Taxus chinensis var. mairei 的化合物4和5在脂肪细胞中显示出显著降低甘油三酯的作用，尽管证据仍处于初步阶段。此外，利用该植物提取物开发的外泌体-cisplatin纳米平台表现出增强的肿瘤靶向性和较低的系统毒性，优于传统方法。Taxus 片剂也显示与注射紫杉醇相当的抗肿瘤疗效，并且具有良好的耐受性，支持其作为潜在口服抗肿瘤药物的发展。含 Taxus chinensis 提取物的 Hongwu 混合物 (HWM) 在 TNBC 细胞中显示出通过 ZNF143 介导 SAV1 激活而降低的存活率和增殖能力。尚未记录该植物的重大安全问题或药物相互作用，但进一步研究对于完全了解其治疗潜力及其作用机制是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究介绍了一种源自红豆杉的外泌体顺铂纳米平台用于治疗三阴性乳腺癌，显示了增强的治疗效果并降低了系统毒性。
- Taxus片剂与PTX注射液在抗肿瘤疗效方面相当，并且耐受性良好，支持其作为口服抗肿瘤药物的发展。
- Hongwu mixture (HWM) inhibited triple-negative breast cancer cell proliferation and promoted apoptosis by regulating ZNF143/SAV1 signaling.
- 来自Taxus chinensis var. mairei的化合物4和5在脂肪细胞中显示出显著降低甘油三酯活性，IC50值与苯氧布特相似。
Frequently asked questions
What is Taxus chinensis?
Taxus chinensis (Taxus chinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Taxus chinensis?
4 sourced findings are recorded for Taxus chinensis; the strongest carries evidence grade D. For example: 这项研究介绍了一种源自红豆杉的外泌体顺铂纳米平台用于治疗三阴性乳腺癌，显示了增强的治疗效果并降低了系统毒性。
How strong is the evidence for Taxus chinensis?
The strongest finding for Taxus chinensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Taxus chinensis safe? What are the side effects?
No major safety issues are recorded for Taxus chinensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Taxus chinensis interact with medications?
No drug interactions are recorded for Taxus chinensis in our sources. This does not rule them out — check with a pharmacist.
Is Taxus chinensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Hongwu mixture exerts inhibition on triple-negative breast cancer by regulating SAV1/Hippo signaling through ZNF143. literature abstract metadata
- T2 A semimechanistic PK/PD model-informed Taxus tablets' development: Accelerating early clinical translation of a taxane-based antitumor agent. literature abstract metadata
- T2 Intelligent plant exosomes synergize miRNAs and cisplatin for spatiotemporally precise multimodal treatment for TNBC with high safety. literature abstract metadata
- T2 2(3→20)-abeo-taxoids with adipogenesis inhibitory activity from the leaves and twigs of Taxus chinensis var. mairei. literature abstract metadata