FolkKB

East Asian groundsel

Tephroseris kirilowii

苔弗罗瑟斯·基里洛维亚是一种传统上与任何已知的医疗实践无关的植物物种。科学研究表明，其分布和种群丰富度在不同植被类型中有所不同，在车前草灌木丛中观察到更高的多样性，而与盐生草地相比。虽然没有报告过传统的用途或针对苔弗罗瑟斯·基里洛维亚进行的广泛医学研究，但该植物提取的一些黄酮类化合物显示出潜在的生物活性，包括对自噬和凋亡途径的调节。这些发现表明某些化合物可能通过PI3Kγ介导的信号通路下调表现出抗增殖作用于人类乳腺癌细胞中。迄今为止，没有记录到苔弗罗瑟斯·基里洛维亚引起的安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自Tephroseris kirilowii的三种黄酮类化合物抑制细胞增殖并诱导凋亡和自噬，通过下调PI3Kγ介导的信号通路在人类乳腺癌细胞中。 D PMID
  • 物种组成在不同植被类型之间差异显著，丰富度最高出现在梭砂灌丛中，最低出现在盐生草甸中。 D PMID
  • 研究发现，日本的 Tephroseris kirilowii 种群在大约 25,000 年前与大陆东亚种群分化开来，并且有冰后期扩张的迹象。 D PMID
  • 苔酚瑟瑞斯·基里洛维的黄酮类化合物被发现可以调节自噬、凋亡和细胞周期。 D PMID

Frequently asked questions

What is East Asian groundsel?

East Asian groundsel (Tephroseris kirilowii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about East Asian groundsel?

4 sourced findings are recorded for East Asian groundsel; the strongest carries evidence grade D. For example: 来自Tephroseris kirilowii的三种黄酮类化合物抑制细胞增殖并诱导凋亡和自噬，通过下调PI3Kγ介导的信号通路在人类乳腺癌细胞中。

How strong is the evidence for East Asian groundsel?

The strongest finding for East Asian groundsel carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is East Asian groundsel safe? What are the side effects?

No major safety issues are recorded for East Asian groundsel in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does East Asian groundsel interact with medications?

No drug interactions are recorded for East Asian groundsel in our sources. This does not rule them out — check with a pharmacist.

What are the common names of East Asian groundsel?

East Asian groundsel is also known as: Пепельник Кирилова.

Is East Asian groundsel a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. literature abstract metadata
  2. T2 A review of biologically active flavonoids as inducers of autophagy and apoptosis in neoplastic cells and as cytoprotective agents in non-neoplastic cells. literature abstract metadata
  3. T2 Phylogeography of the temperate grassland plant Tephroseris kirilowii (Asteraceae) inferred from multiplexed inter-simple sequence repeat genotyping by sequencing (MIG-seq) data. literature abstract metadata
  4. T2 Canopy-Mediated Shifts in Grassland Diversity and Heterogeneity: A Power Law Approach from China's Loess Plateau. literature abstract metadata