FolkKB

East Asian groundsel

Tephroseris kirilowii

苔弗罗瑟斯·基里洛维亚是一种传统上未用于任何已知医疗实践的植物。科学研究表明，该物种中的黄酮类化合物可以通过下调PI3Kγ信号通路，在人类乳腺癌细胞中抑制细胞增殖并诱导凋亡和自噬，这表明其具有潜在的抗癌作用。该物种在不同植被类型中的组成差异很大，其中最高丰富度出现在日本沙棘灌木林中。遗传研究表明，日本苔弗罗瑟斯·基里洛维亚种群大约25,000年前从大陆东亚种群分化出来，并经历了冰后期扩张。尽管没有记录到重大安全问题或药物相互作用的证据，但当前的科学发现仅限于体外研究，因此需要进一步的研究来确认这些潜在效果。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自Tephroseris kirilowii的三种黄酮类化合物抑制细胞增殖并诱导凋亡和自噬，通过下调PI3Kγ介导的信号通路在人类乳腺癌细胞中。 D PMID
  • 物种组成在不同植被类型之间差异显著，丰富度最高出现在梭砂灌丛中，最低出现在盐生草甸中。 D PMID
  • 研究发现，日本的 Tephroseris kirilowii 种群在大约 25,000 年前与大陆东亚种群分化开来，并且有冰后期扩张的迹象。 D PMID
  • 苔酚瑟瑞斯·基里洛维的黄酮类化合物被发现可以调节自噬、凋亡和细胞周期。 D PMID

Frequently asked questions

What is East Asian groundsel?

East Asian groundsel (Tephroseris kirilowii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about East Asian groundsel?

4 sourced findings are recorded for East Asian groundsel; the strongest carries evidence grade D. For example: 来自Tephroseris kirilowii的三种黄酮类化合物抑制细胞增殖并诱导凋亡和自噬，通过下调PI3Kγ介导的信号通路在人类乳腺癌细胞中。

How strong is the evidence for East Asian groundsel?

The strongest finding for East Asian groundsel carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is East Asian groundsel safe? What are the side effects?

No major safety issues are recorded for East Asian groundsel in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does East Asian groundsel interact with medications?

No drug interactions are recorded for East Asian groundsel in our sources. This does not rule them out — check with a pharmacist.

What are the common names of East Asian groundsel?

East Asian groundsel is also known as: Пепельник Кирилова.

Is East Asian groundsel a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. literature abstract metadata
  2. T2 A review of biologically active flavonoids as inducers of autophagy and apoptosis in neoplastic cells and as cytoprotective agents in non-neoplastic cells. literature abstract metadata
  3. T2 Phylogeography of the temperate grassland plant Tephroseris kirilowii (Asteraceae) inferred from multiplexed inter-simple sequence repeat genotyping by sequencing (MIG-seq) data. literature abstract metadata
  4. T2 Canopy-Mediated Shifts in Grassland Diversity and Heterogeneity: A Power Law Approach from China's Loess Plateau. literature abstract metadata