Bootlace Plant
Wikstroemia indica
Wikstroemia indica，这种植物传统上在亚洲医学中使用，特别是在阿育吠陀和中国传统医学中。尽管其具体用途尚未得到充分记录。科学研究表明，从该植物中提取的活性成分daphnoretin具有抗肿瘤作用，能够抑制结肠癌细胞的增殖和迁移。此外，从Wikstroemia indica中分离出的八种化合物被发现可以减少炎症并抑制脊髓损伤小鼠模型中的NF-κB信号通路激活。预计气候变化将使该植物在中国西北部适宜生长区域扩大。尚未记录与这种植物相关的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自维克斯特罗米亚印弟卡的达芬雷汀通过HSP90AA1靶向作用增强P53泛素化，抑制结肠癌细胞增殖和迁移。
- 从Wikstroemia indica中分离出了8个化合物，其中一个显著减少了巨噬细胞中的IL-1β分泌。
- 达芬雷汀抑制了脊髓损伤小鼠的炎症和NF-κB途径激活。
- 研究发现，气候变化预计将显著扩大和改变中国北部地区Wikstroemia indica适宜生境的范围。
Frequently asked questions
What is Bootlace Plant?
Bootlace Plant (Wikstroemia indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bootlace Plant?
4 sourced findings are recorded for Bootlace Plant; the strongest carries evidence grade D. For example: 来自维克斯特罗米亚印弟卡的达芬雷汀通过HSP90AA1靶向作用增强P53泛素化，抑制结肠癌细胞增殖和迁移。
How strong is the evidence for Bootlace Plant?
The strongest finding for Bootlace Plant carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bootlace Plant safe? What are the side effects?
No major safety issues are recorded for Bootlace Plant in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bootlace Plant interact with medications?
No drug interactions are recorded for Bootlace Plant in our sources. This does not rule them out — check with a pharmacist.
Is Bootlace Plant a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Daphnoretin inhibited SCI-induced inflammation and activation of NF-κB pathway in spinal dorsal horn. literature abstract metadata
- T2 Lignans and neolignans from the twigs and leaves of Wikstroemia indica (L.) C.A. Mey. with their effects on LPS-induced IL-1β and IL-10 secretion in RAW 264.7 macrophages. literature abstract metadata
- T2 Projected Expansion and Northwestern Shift of Wikstroemia indica Suitable Habitats in China Under Multiple Climate Change Scenarios: An Optimized MaxEnt Approach. literature abstract metadata
- T2 Daphnoretin targeted binding to HSP90AA1 to promote P53 UFMylation and stability thereby inducing apoptosis in colorectal cancer. literature abstract metadata